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Digestive Disease Interventions
DOI: 10.1055/s-0045-1807733
DOI: 10.1055/s-0045-1807733
Review Article
Image-Guided Percutaneous Biopsy of the Pancreas

Abstract
Image-guided percutaneous biopsy of the pancreas is a valuable diagnostic tool for evaluating pancreatic lesions. This article provides an overview of the techniques involved, indications for biopsy, and the role of imaging modalities, potential complications, and patient outcomes. By integrating a multidisciplinary approach and advanced imaging technologies, clinicians who manage patients with pancreatic lesions can enhance diagnostic accuracy and patient management.
Publication History
Received: 18 November 2024
Accepted: 18 March 2025
Article published online:
23 May 2025
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References
- 1 Hartwig W, Schneider L, Diener MK, Bergmann F, Büchler MW, Werner J. Preoperative tissue diagnosis for tumours of the pancreas. Br J Surg 2009; 96 (01) 5-20
- 2 Bhatti I, Ojo D, Dennison AR, Rees Y, Elabassy M, Garcea G. Percutaneous pancreatic biopsies - still an effective method for histologic confirmation of malignancy. Surg Laparosc Endosc Percutan Tech 2016; 26 (04) 334-337
- 3 Kwan MC, Zhang ML. Pancreas fine needle aspiration: current and future impact on patient care. Surg Pathol Clin 2024; 17 (03) 441-452
- 4 Orth M, Metzger P, Gerum S. et al. Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches. Radiat Oncol 2019; 14 (01) 141
- 5 Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin 2024; 74 (01) 12-49
- 6 Planz V, Galgano SJ. Percutaneous biopsy and drainage of the pancreas. Abdom Radiol (NY) 2022; 47 (08) 2584-2603
- 7 Erturk SM, Mortelé KJ, Tuncali K, Saltzman JR, Lao R, Silverman SG. Fine-needle aspiration biopsy of solid pancreatic masses: comparison of CT and endoscopic sonography guidance. AJR Am J Roentgenol 2006; 187 (06) 1531-1535
- 8 Chai WL, Kuang XF, Yu L. et al. Percutaneous ultrasound and endoscopic ultrasound-guided biopsy of solid pancreatic lesions: an analysis of 1074 lesions. Hepatobiliary Pancreat Dis Int 2023; 22 (03) 302-309
- 9 Turgut B, Bakdik S, Öncü F. et al. Diagnostic yield of transabdominal ultrasound-guided core needle method in biopsies of pancreatic lesions. Ultrasound Q 2023; 39 (02) 109-116
- 10 Caymaz I, Afandiyeva N. Diagnostic evaluation of solid pancreatic lesions: endoscopic ultrasound-guided fine needle aspiration versus percutaneous ultrasound-guided core needle biopsy. Cardiovasc Intervent Radiol 2023; 46 (11) 1596-1602
- 11 Chung SH, Kang HJ, Lee HJ, Kim JS, Lee JK. Safety and efficacy of ultrasound-guided percutaneous core needle biopsy of pancreatic and peripancreatic lesions adjacent to critical vessels. Daehan Yeongsang Uihakoeji 2021; 82 (05) 1207-1217
- 12 Stella SF, Van Borsel M, Markose G, Nair SB. Image-guided percutaneous biopsy for pancreatic lesions: 10-year experience in a tertiary cancer center. Can Assoc Radiol J 2019; 70 (02) 199-203
- 13 Su YY, Liu YS, Chao YJ, Chiang NJ, Yen CJ, Tsai HM. Percutaneous computed tomography-guided coaxial core biopsy for the diagnosis of pancreatic tumors. J Clin Med 2019; 8 (10) 1633
- 14 Gruber-Rouh T, Langenbach MC, Eichler K, Vogl TJ, Yel I, Beeres M. CT-guided percutaneous biopsy of suspect pancreatic lesions: radiological and clinical outcome. Clin Radiol 2019; 74 (11) 899.e7-899.e12
- 15 Tyng CJ, Almeida MF, Barbosa PN. et al. Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis. World J Gastroenterol 2015; 21 (12) 3579-3586
- 16 Rosiak G, Franke J, Milczarek K, Konecki D, Bielecki DK, Januszewicz M. Computed tomography-guided percutaneous biopsy of pancreatic masses. Pol Arch Intern Med 2024; 134 (05) 16727
- 17 Tchercansky A, Fernandez Alberti J, Arrechea Antelo R, Bregante ML, Pirchi DE. Diagnostic yield of computed tomography guided fine-needle aspiration for pancreatic cancer. Medicina (B Aires) 2022; 82 (05) 708-713
- 18 Zhang F, Jin G, Dai M, Ding M, Zhang J, Zhang X. Percutaneous magnetic resonance imaging-guided coaxial cutting needle biopsy of pancreatic lesions: diagnostic accuracy and safety. Cardiovasc Intervent Radiol 2023; 46 (11) 1603-1609
- 19 Atwell TD, Smith RL, Hesley GK. et al. Incidence of bleeding after 15,181 percutaneous biopsies and the role of aspirin. AJR Am J Roentgenol 2010; 194 (03) 784-789
- 20 Mueller M, Mason RA, Kratzer W, Oeztuerk S, Haenle MM. Sonographically guided puncture of the pancreas: incidence of complications, and risk factors. J Med Ultrason 2013; 40 (01) 19-26
- 21 Mueller PR, Miketic LM, Simeone JF. et al. Severe acute pancreatitis after percutaneous biopsy of the pancreas. AJR Am J Roentgenol 1988; 151 (03) 493-494
- 22 Tseng HS, Chen CY, Chan WP, Chiang JH. Percutaneous transgastric computed tomography-guided biopsy of the pancreas using large needles. World J Gastroenterol 2009; 15 (47) 5972-5975
- 23 Young R, Gagandeep S, Grant E. et al. Gastroduodenal artery pseudoaneurysm secondary to pancreatic head biopsy. J Ultrasound Med 2004; 23 (07) 997-1001