J Neurol Surg B Skull Base 2025; 86(S 01): S1-S576
DOI: 10.1055/s-0045-1803576
Presentation Abstracts
Podium Presentations
Poster Presentations

Nontraditional Approaches to Reconstruction of Large Anterior Skull Base and Midface Defects

Travis Clarke
1   University of Tennessee Health Science Center, Memphis, Tennessee, United States
,
Aaron Zebolsky
1   University of Tennessee Health Science Center, Memphis, Tennessee, United States
,
Anas Eid
1   University of Tennessee Health Science Center, Memphis, Tennessee, United States
› Author Affiliations
 
 

    Introduction: Large anterior skull base and midface defects pose significant challenges to the reconstructive surgeon, often requiring a multidisciplinary approach to achieve an optimal outcome. Defects of this nature can result from various etiologies including trauma, oncologic resection and congenital abnormalities. Reconstruction of these defects requires a thorough understanding of the anatomical and functional relationships of the midface and anterior skull base the goal of this study is to present 2 cases of significant skull base defects and review the decision-making process for reconstructing these defects.

    Methods: A case-centric approach was employed for this study.

    Case 1: A 26-year-old male patient presented with a T4 mesenchymal chondrosarcoma of the nasal cavity, which had invaded the anterior skull base.

    Case 2: A 22-year-old male patient suffered a gunshot wound (GSW) to the midface, resulting in significant midfacial deformity and an anterior skull base defect.

    Results: Both patients had large midface deformities and anterior skull base defects that required significant reconstruction. Our approach to these patients was a multistage approach. The goal of the first stage was to restore soft tissue bulk with a soft tissue flap such as the anterolateral thigh free flap with the goal to seal any dural skull base defects. Later stages are reserved for reconstruction of anatomical units of the nose and NOE segments and optimizing aesthetic results.

    Conclusion: Reconstruction of large anterior skull base and midface defects is a complex and challenging process. The two case reports presented demonstrate the use of staged reconstruction soft tissue and osseus-free flaps and highlights and an algorithm for managing these challenging defects. Further research is needed to optimize reconstructive outcomes and minimize morbidity in these patients.


    No conflict of interest has been declared by the author(s).

    Publication History

    Article published online:
    07 February 2025

    © 2025. Thieme. All rights reserved.

    Georg Thieme Verlag KG
    Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany