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Digestive Disease Interventions 2024; 08(04): 263-271
DOI: 10.1055/s-0044-1787959
Review Article

Image-Guided Ablation for Cholangiocarcinoma: Current Evidence and Future Directions

Authors

  • Jessica Albuquerque M. Silva 

    1   Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas

  • Iwan Paolucci

    1   Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas

  • Kristy K. Brock

    2   Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas

  • Bruno C. Odisio

    1   Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas

Funding Sources The present manuscript has no funding support.Researchers on this publication were supported in part by the National Cancer Institute of the National Institutes of Health under award number R01CA235564; the Image Guided Cancer Therapy Research Program at The University of Texas MD Anderson Cancer Center through a generous gift from the Apache Corporation and the Helen Black Image Guided Fund, by the Tumor Measurement Initiative through the MD Anderson Strategic Initiative Development Program (STRIDE), and Siemens Healthineers.
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Abstract

Though the incidence of intrahepatic cholangiocarcinoma (ICC) is rare compared with other malignancies, its prevalence is increasing significantly worldwide. Intrahepatic cholangiocarcinoma is an aggressive tumor, typically presenting at an advanced stage and showing resistance to treatments. The primary cause of mortality is liver failure related to tumor progression with associated parenchymal loss and vascular or biliary compromise. Currently, surgical resection remains the primary curative approach, yet less than 20% of patients are eligible for such treatment, and postoperative rate of recurrence are high. In this context, locoregional therapies such as percutaneous thermal ablation have been shown to be safe and effective for patients with unresectable or recurrent ICCs. This review discusses the clinical application of ablation techniques, as it relates to patient selection and tumor characteristics for the treatment of ICC.

Keywords

ablation techniques - cholangiocarcinoma - liver

Authors' Contributions

1. Contributions to conception and design, acquisition of data, or analysis and interpretation of data: all authors.


2. Drafting and revising the article: J.A.M.S., I.P., B.C.O.


4. Final approval of the version to be published: all authors.




Publication History

Received: 04 April 2024

Accepted: 30 May 2024

Article published online:
13 August 2024

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