Antioxidant activity from leaves of Cochlospermum angolense

Cochlospermum angolense Welw. ex Oliv, commonly known as Borututu, is an endemic plant from Angola. This medicinal plant belongs to the Cochlospermaceae family and is used in traditional medicine for treating malaria, diabetes and other diseases. This is a plant of biological interest and its antioxidant activity and chemical profile have been described in this study. Antioxidant activity of three extracts (hexane, acetone and ethanol) from leaves of C. Angolenses, were determinated by three diferent methods: 1) DPPH radical scavenging activity; 2) in vitro evaluation of the superoxide anion trapping capacity in a non-enzymatic system; 3) nitric oxide radical scavenging activity.

As shown in [Table 1], the results suggest strong antioxidant activity for this species. The ethanol and acetone extracts of leaves developed antiradical activity against DPPH, obtaining an inhibition near 80%. These results are very similar to those obtained for quercetin standard. The ●O−radical scavenging activity of acetone and ethanol extracts presented inhibitory effects similar to quercetin. The hexane extract did not show activity indicating an inhibition of reactive oxygen species. Against the radical NO, the ethanol extract presents higher inhibitory activity comparing to the standards. Compounds with hydroxyl groups, from acetone and ethanol extracts, could explain this strong antioxidant activity.

Table 1 Antioxidant activity from leaves of C. angolense.

Publikationsverlauf

Artikel online veröffentlicht:
16. November 2023