Aims Endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for hepatic solid lesions
has emerged as a safe technique to diagnosis. However, the optimal FNB techniques
have not been evaluated. Our study aimed to compare the diagnostic yield and specimen
adequacy of EUS-FNB in hepatic solid lesions using different FNB techniques ([Table 1]).
Table 1 Diagnostic performances according to EUS-FNB techniques.
Methods This is a single center retrospective study of EUS-FNB for hepatic solid lesions
between Mar. 2015 and Jun. 2022. Each one needle pass of suction and slow-pull suction
was applied for same hepatic lesions and the sequence was randomly assigned. The primary
outcomes were diagnostic yield to attain a histological diagnosis and rate of adequate
specimen acquisition.
Results A total of 119 patients (40 females, median age 70 years) underwent EUS-FNB for hepatic
solid lesions. The mean lesion size was 34.9±27.3 mm (range 7-150). The overall diagnostic
yield was 90.8%. There was statistically no difference in diagnostic accuracy between
suction and slow-pull suction (79.8% vs. 84.9%, P=0.308). Slow-pull suction obtained
more adequate specimen comparing to suction (95.0% vs. 87.4%, P=0.040) [1]
[2].
Conclusions The use of slow-pull suction EUS-FNB demonstrated improved specimen adequacy compared
with suction technique with no difference in diagnostic accuracy.
