Informationen der Gesellschaft für Pädiatrische Radiologie zur Verwendung von gadoliniumhaltigem Kontrastmittel für die Kernspintomografie im Kindes- und Jugendalter

• Literatur

• 1 Thomson HS, Webb AW. (eds) Contrast Media: Safety issues and ESUR guidelines. 3rd ed. Berlin-New York: Springer; 978-3-642-36723-6, 245-251
• 2 Riccabona M, Olsen OE, Claudon M. et al. Gadolinium and nephrogenic systemic fibrosis. In: Fotter R. (ed.) Pediatric uroradiology. 2nd Edtition. Berlin-Heidelberg- NewYork: Springer; 2008: 515-517
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• 4 Rogosnitzky M, Branch S. Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms. Biometals 2016; 29: 365-376
• 5 Frenzel T, Lengsfeld P, Schirmer H. et al. Stability of gadolinium-based magnetic resonance imaging contrast agents in human serum at 37 degrees C. Investigative radiology 2008; 43: 817-828
• 6 Thomsen HS, Morcos SK, Almén T. et al. Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Medium Safety Committee guidelines. European radiology 2013; 23: 307-318
• 7 McDonald RJ, McDonald JS, Kallmes DF. et al. Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging. Radiology 2015; 275: 772-782
• 8 Kanda T, Ishii K, Kawaguchi H. et al. High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-weighted MR Images: Relationship with Increasing Cumulative Dose of a Gadolinium-based Contrast Material Radiology. Radiology 2014; 270: 834-841
• 9 Errante Y, Cirimele V, Mallio CA. et al. Progressive Increase of T1 Signal Intensity of the Dentate Nucleus on Unenhanced Magnetic Resonance Images Is Associated With Cumulative Doses of Intravenously Administered Gadodiamide in Patients With Normal Renal Function, Suggesting Dechelation. Investigative radiology 2014; 49: 685-690
• 10 Quattrocchi CC, Mallio CA, Errante Y. et al. Gadodiamide and Dentate Nucleus T1 Hyperintensity in Patients With Meningioma Evaluated by Multiple Follow-Up Contrast-Enhanced Magnetic Resonance Examinations With No Systemic Interval Therapy. Investigative radiology 2015; 50: 470-472
• 11 Roberts DR, Holden KR. Progressive increase of T1 signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images in the pediatric brain exposed to multiple doses of gadolinium contrast. Brain and Development 2016; 38: 331-336
• 12 Miller JH, Hu HH, Pokorney A. et al. MRI Brain Signal Intensity Changes of a Child During the Course of 35 Gadolinium Contrast Examinations. Pediatrics 2015; 136: e1637-e1640
• 13 Flood TF, Stence NV, Maloney JA. et al. Pediatric Brain: Repeated Exposure to Linear Gadolinium-based Contrast Material Is Associated with Increased Signal Intensity at Unenhanced T1-weighted MR Imaging. Radiology 2017; 282: 222-228
• 14 Hu HH, Pokorney A, Towbin RB. et al. Increased signal intensities in the dentate nucleus and globus pallidus on unenhanced T1-weighted images: evidence in children undergoing multiple gadolinium MRI exams. Pediatr Radiol 2016; 46: 1590-1598
• 15 Radbruch A, Weberling LD, Kieslich PJ. et al. Gadolinium retention in the dentate nucleus and globus pallidus is dependent on the class of contrast agent. Radiology 2015; 275: 783-791
• 16 Kanda T, Osawa M, Oba H. et al. High Signal Intensity in Dentate Nucleus on Unenhanced T1-weighted MR Images: Association with Linear versus Macrocyclic Gadolinium Chelate Administration. Radiology 2015; 275: 803-809
• 17 Robert P, Violas X, Grand S. et al. Linear Gadolinium-Based Contrast Agents Are Associated With Brain Gadolinium Retention in Healthy Rats. Investigative radiology 2016; 51: 73-82
• 18 Stojanov DA, Aracki-Trenkic A, Vojinovic S. et al. Increasing signal intensity within the dentate nucleus and globus pallidus on unenhanced T1W magnetic resonance images in patients with relapsing-remitting multiple sclerosis: correlation with cumulative dose of a macrocyclic gadolinium-based contrast agent, gadobutrol. European radiology 2016; 26: 807-815
• 19 Stojanov D, Aracki-Trenkic A, Benedeto-Stojanov D. Gadolinium deposition within the dentate nucleus and globus pallidus after repeated administrations of gadolinium-based contrast agents-current status. Neuroradiology 2016; 58: 433-441
• 20 Murata N, Gonzalez-Cuyar LF, Murata K. et al. Macrocyclic and Other Non-Group 1 Gadolinium Contrast Agents Deposit Low Levels of Gadolinium in Brain and Bone Tissue: Preliminary Results From 9 Patients With Normal Renal Function. Investigative radiology 2016; 51: 447-453
• 21 Bussi S, Fouillet X, Morisetti A. Toxicological assessment of gadolinium release from contrast media. Experimental and toxicologic pathology: official journal of the Gesellschaft für Toxikologische Pathologie 2007; 58: 323-330
• 22 Rogosnitzky M, Branch S. Gadolinium-based contrast agent toxicity: a review ofknown and proposed mechanisms. Biometals 2016; 29: 365-376 ; Epub 2016 Apr 6. Review
• 23 Malayeri AA, Brooks KM, Bryant LH. et al. National Institutes of Health Perspective on Reports of Gadolinium Deposition in the Brain. J Am Coll Radiol 2016; 13: 237-241 ; Epub 2016 Jan 23