Optimization of lavender distillation process by studying the essential oilʼs chemical composition and antioxidant activity

A Nakas; G Giannarelli; A Peperidou; I Fotopoulos; E Chainoglou; K N Kontogiannopoulos; A Tsiaprazi-Stamou; V Varsamis; H Gika; D Hadjipavlou-Litina; A Ν Assimopoulou

doi:10.1055/s-0042-1759183

Planta Medica, Table of Contents

Planta Med 2022; 88(15): 1510-1511
DOI: 10.1055/s-0042-1759183

Poster Session II

Optimization of lavender distillation process by studying the essential oilʼs chemical composition and antioxidant activity

A Nakas∗

¹Laboratory of Organic Chemistry, School of Chemical Engineering, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

³Natural Products Research Centre of Excellence, Center for Interdisciplinary Research and Innovation of Aristotle University of Thessaloniki, 57001, Thessaloniki, Greece

,

G Giannarelli

¹Laboratory of Organic Chemistry, School of Chemical Engineering, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

,

A Peperidou

²Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

,

I Fotopoulos

²Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

,

E Chainoglou

²Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

,

K N Kontogiannopoulos

¹Laboratory of Organic Chemistry, School of Chemical Engineering, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

³Natural Products Research Centre of Excellence, Center for Interdisciplinary Research and Innovation of Aristotle University of Thessaloniki, 57001, Thessaloniki, Greece

,

A Tsiaprazi-Stamou

⁴Vessel Essential Oils, Neo Rysio, 57001, Thessaloniki, Greece

,

V Varsamis

⁴Vessel Essential Oils, Neo Rysio, 57001, Thessaloniki, Greece

,

H Gika

³Natural Products Research Centre of Excellence, Center for Interdisciplinary Research and Innovation of Aristotle University of Thessaloniki, 57001, Thessaloniki, Greece

⁵School of Medicine, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

,

D Hadjipavlou-Litina

²Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

,

A Ν Assimopoulou

¹Laboratory of Organic Chemistry, School of Chemical Engineering, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece

³Natural Products Research Centre of Excellence, Center for Interdisciplinary Research and Innovation of Aristotle University of Thessaloniki, 57001, Thessaloniki, Greece

› Author Affiliations

Abstract

Full Text

Lavandula angustifolia (common name lavender) is a flowering plant of the Lamiaceae family and among the most valuable aromatic and medicinal plants for perfumery, cosmetics, pharmaceutical, agricultural and food industry [1].

Aim of the present study was to find the appropriate pilot scale distillation conditions that optimize the yield and pleasant aroma of the essential oil (EO) of lavender cultivated in northern Greece. Specifically, all steam distillations were conducted at the industrial distillery “Vessel Essential Oils” and process parameters were: time, temperature and pressure, implementing a Face-Centered Composite experimental design.

EOsʼ composition was determined by Headspace GC-MS analysis. Prior to the final analyses, pretreatment, sampling, chromatography and MS conditions were optimized. The in vitro antioxidant activity of EOs from all distillation conditions was evaluated via the inhibition of linoleic acid peroxidation assay, as well as through the soybean lipoxygenase inhibition study to investigate the anti-inflammatory activity [2], [3].

With the applied GC-MS method, more than 35 volatile compounds were identified in the lavenderʼs EOs, and their relative percentages were recorded. The desired space was determined by applying a three-dimensional response surface analysis of the independent and dependent variables, selecting as optimization criteria the EOʼs yield, along with the relative abundance of linalool, which is the primary compound responsible for lavenderʼs pleasant fragrance.

This research has been co-financed by the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation, under the call RESEARCH–CREATE–INNOVATE (project code: T1EDK-04174).

The authors declare that they have no conflict of interest.

References

References
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2 Kouzi O, Pontiki E, Hadjipavlou-Litina D. 2-Arylidene-1-indandiones as Pleiotropic Agents with Antioxidant and Inhibitory Enzymes Activities. Molecules 2019; 24: 4411
3 Pontiki E, Hadjipavlou-Litina D. Multi-Target Cinnamic Acids for Oxidative Stress and Inflammation: Design, Synthesis, Biological Evaluation and Modeling Studies. Molecules 2018; 24: 12