Keywords
dental occlusion - quality of life - xerostomia
Introduction
Thus far, quality of life assessment is mostly based on the general health of people.[1]
[2] Oral health might play a considerable role in determining life quality. Quality
of life itself cannot be separated from the overall condition of a human being, which
comprises general and oral health.[3] Health and function of the mouth deteriorate with age.[4] Poor oral conditions among elderly people are particularly influenced by edentulism,
dental caries, periodontal disease, xerostomia, salivary gland dysfunction, and oral
mucosal lesions, including premalignant lesions.[5]
[6] These conditions severely impact the daily life of elderly people and decrease their
oral function, self-confidence, and social life. This decline eventually affects the
oral health-related quality of life (OHRQoL),[5]
[7] which reflects the satisfaction of people with respect to oral functions, such as
eating, sleeping, and engaging in social interaction, as well as their self-esteem.[8] OHRQoL is assessed by studying how factors such as function, pain, and psychological
and social aspects affect the well-being of an individual.[9]
This type of research is essential in Indonesia because Indonesian populations can
be categorized into old age groups; the percentage of elders reached 7% in 2010 and
will continuously increase up to 14.1% in 2030[10]
[11] and 15.8% (an increase of 8.2%) by 2035.[12] The number of Indonesian elders is predicted to become the highest in the world.[13] Yogyakarta is one of the provinces in Indonesia with the highest number of elders.
Around 14% of the populations in Yogyakarta are elders.[10]
[12] Yogyakarta is also a city with the longest life expectancy in Indonesia; therefore,
many elderly associations are rapidly growing in this area.[11]
[12] A previous preliminary study demonstrated that around 70% of elders in Yogyakarta
had low OHRQoL.
Old age may contribute to several health problems either as a result of physiologic
(degenerative) or pathologic processes. Elderly people may be susceptible to acute
or chronic disease due to their decreasing immune system, thus making them consume
additional medications. Deterioration of physiologic condition, polypharmacy, and
the high occurrence of chronic diseases in elders may manifest in unavoidable oral
cavities.[14] The only possible approach is to minimize their effects to help elders increase
their quality of life regardless of their health condition.
Xerostomia (dry mouth) either with or without hyposalivation is one of the common
oral manifestations complained about by elders. Reports indicate that 80% of prescribed
medications cause xerostomia.[15]
[16]
[17]
[18] Xerostomia and hyposalivation easily contribute to the development of poor oral
hygiene, dental caries, and periodontal disease due to the reduced function of saliva.[17]
[18] Dental caries and periodontal disease are the main causes of tooth loss. Thus, tooth
loss without rehabilitative treatment results in mastication impairment, which, in
turn, affects OHRQoL. A previous study in Yogyakarta found that 69.85% of the elderly
had poor oral OHRQoL (2013, unpublished research). From the study was found as well
that the majority of elderly oral health was poor, but when the OHRQoL assessment
was carried out, it turned out that the OHRQoL was still satisfactory. For this reason,
it is very important identifying oral conditions that may be potential risk factors
for the low OHRQoL of elders in Yogyakarta, which was the aim of this study. The implications
of this study will help the government in planning and improving oral health management
for elders, which is expected to increase their OHRQoL.
Materials and Methods
Participants
This observational cross-sectional study involved 153 participants (≥60 years) comprising
39 males and 114 females from five elderly associations (Posyandu Lansia) from three subdistricts in Yogyakarta with a high number of elderly (Danurejan,
Gedongtengen, and Jetis). The five Posyandu Lansia (Kemetiran, Gowongan, Suryatmajan, Tegalpanggung, and Danurejan) were randomly chosen
from these subdistricts. Inclusion criteria of participants: people who are ≥60 years
of age and can hear and communicate well.
To recruit the participants, forty letters of invitation to this survey were mailed
for each Posyandu Lansia, so 200 letters of invitation were addressed to people aged 60 years and over. All
recipients were informed about the aim and study course. Appointment for the examination
was given for individuals upon submission of their written informed consent as their
agreement to be involved in this research. There were 176 positive responders, after
the invitation. Eighteen persons of 176 positive responders did not come to the examination
venue due to some reasons, i.e., 8 persons with urgent personal matters and 10 persons
with obstacles in transportation. The other five persons came to the examination venue
but with incomplete data due to incomplete questionnaire filling because of difficulty
in communicating, listening, and capturing questions. Finally, there were 153 participants
involved in this research as study subjects. None of the participants required special
assistance for their daily activities.
Ethics approval for conducting this study has been obtained from the Ethics Committee
of the Dentistry Faculty, Universitas Gadjah Mada, Yogyakarta, Indonesia (Approval
number: 683/KKEP/FKG-UGM/EC/2014).
Measurements
The participants underwent intraoral examination to assess oral hygiene (OH), periodontal
tissue condition, DMFT index (the number of decayed, missing, and filled teeth), and
the number of natural occluding pairs (NOP) of teeth.
Oral hygiene was determined using OHI-S developed by Greene and Vermillion with the
aid of the no. 5 explorer that was moved along the examined tooth surface. The OH
score was classified as 0.0–1.2 (good), 1.3–3.0 (fair), and 3.1–6.0 (poor). The condition
of the periodontal tissue was evaluated using the WHO periodontal probe with a round
tip of 0.5 mm diameter. The Community Periodontal Index of the WHO was applied. The
score of the periodontal tissue condition was classified into the following: 0 (healthy
tissue), 1 (bleeding of probing), 2 (calculus with a plaque by probing), 3 (4–5 mm
of pathologic pocket), and 4 (≥6 mm of pathologic pocket). The status of periodontal
tissue each tooth was determined according to the highest classification. The number
of DMFT was determined using the DMFT index, and the examination was clinically performed
using dental diagnostic instruments. The number of NOP of teeth was also clinically
examined and counted. Each examination helped determine the oral health status of
the participants and was used as an oral health status indicator.
OHRQoL was determined using GOHAI.[19] The 12-item questionnaire of GOHAI was developed in the Indonesian version after
validity and reliability tests were done (r = 0.287, p < 0.05; Cronbach's alpha coefficient = 0.783) to assess the following three dimensions
of OHRQoL: physical function, pain or discomfort, and psychosocial function. This
questionnaire comprises a six-point Likert scale from never, rarely, occasionally,
fairly often, very often to always. The final score ranges from 0 to 60, wherein a
high score indicates an improved OHRQoL. The GOHAI score was classified as high (57–60),
moderate (51–56), and low (≤50). Xerostomia was determined by interviewing participants
about the history of dry mouth in the past three months on the Xerostomia Inventory
(XI) in the Indonesian version after validity and reliability tests were done (r = 0.295, p < 0.05; Cronbach's alpha coefficient = 0.890), which comprises an 11-item questionnaire
covering experiential and behavioral aspects of xerostomia. The questionnaire comprises
a five-point Likert scale from never, hardly ever, occasionally, fairly often to very
often.[20] Xerostomia was determined when participants answered “fairly often” and/or “very
often”.[21] Hyposalivation (volume of saliva <0.1 ml/min) was identified by measuring whole
unstimulated saliva flow using the spitting method. In this study, measurement of
DMFT and oral hygiene were conducted by FN, and measurement of periodontal status
and NOP were conducted by BEC for all participants. Four professional students of
the Faculty of Dentistry Universitas Gadjah Mada helped FN and BEC in writing the
measurement results in Oral Health Status Forms. Filling in the questionnaires of
GOHAI and XI by interviewing all participants was carried out by DA. Measuring salivary
flow for all participants was done by DA with the assistance of other four professional
students of the Faculty of Dentistry, Universitas Gadjah Mada to weigh the saliva
and write the measurement results in Oral Health Status Forms. Measuring the salivary
flow was conducted from 8 a.m. to 10 a.m.
Statistical Analysis
For statistical analyses, the results of variable measurements were categorized as
low OHRQoL if the GOHAI score of ≤50, and high OHRQoL if the GOHAI score > 50. Xerostomic
status was categorized as xerostomia and non xerostomia. Hyposalivation status was
categorized as hyposalivation and nonhyposalivation. Oral hygiene status was categorized
as poor oral hygiene if the OHI-S score of ≥3.1, and good oral hygiene if the OHI-S
score < 3.1. NOP status was categorized as NOP ≤5 and NOP >5. DMFT Index was categorized
as high if the DMFT Index >13.9 and low if the DMFT Index ≤13.9. The periodontal pocket
was determined if the classification of CPI were 3 and 4, meanwhile periodontal status
was determined not having a periodontal pocket if the classification of CPI were 0,
1, and 2.
Bivariate and multivariate analyses were conducted using SPSS software 16.0 version
(IBM Corp., Chicago) to estimate the risk factors for low OHRQOL.
Results
The results from the subject's characteristics based on OHRQoL in [Table 1] demonstrated that only gender (p = 0.024) and occupation (p = 0.028) had significant
contributions to the proportion of the OHRQoL status. Female subjects had a more significant
proportion of poor OHRQoL status compared to male subjects. Formal worker subjects
had a more significant proportion of poor OHRQoL status compared to the other two
occupations (household worker and informal worker).
Table 1
Subject's characteristics based on OHRQoL (N = 153)
No.
|
Variable
|
OHRQoL
|
p-Value*
|
n (%)
|
Poor
|
Good
|
1.
|
Gender
|
|
|
0.024
|
|
Male
|
22 (20.4)
|
17 (37.8)
|
|
|
Female
|
86 (79,6)
|
28 (62.2)
|
|
2.
|
Education
|
|
|
0.786
|
|
Non-formal education
|
31 (28.7)
|
10 (22.2)
|
|
|
Elementary school
|
20 (18.5)
|
10 (22.2)
|
|
|
Junior high school
|
37 (34.3)
|
14 (31.3)
|
|
|
Senior high school
|
13 (12)
|
6 (13.3)
|
|
|
University/college
|
7 (6.5)
|
5 (11.1)
|
|
3.
|
Residential
|
|
|
0.476
|
|
Rural
|
30 (27.8)
|
10 (22.2)
|
|
|
Urban
|
78 (72.2)
|
35 (77.8)
|
|
4.
|
Ethnicity
|
|
|
0.153
|
|
Javanese
|
107 (99.1)
|
43 (95.6)
|
|
|
Non-Javanese
|
1 (0.9)
|
2 (4.4)
|
|
5.
|
Marital Status
|
|
|
0.779
|
|
Widowed
|
61 (56.5)
|
28 (62.2)
|
|
|
Married
|
45 (41.7)
|
16 (35.6)
|
|
|
Not-married
|
2 (1.9)
|
1 (2.2)
|
|
6.
|
Occupation
|
|
|
0.028
|
|
Household worker
|
39 (36.1)
|
11 (24.4)
|
|
|
Informal worker
|
13 (12)
|
1 (2.2)
|
|
|
Formal worker
|
56 (51.9)
|
33 (73.3)
|
|
7.
|
Systemic disease
|
|
|
0.983
|
|
No systemic disease
|
53 (49.1)
|
22 (48.9)
|
|
|
Systemic disease
|
55 (50.9)
|
23 (51.1)
|
|
8.
|
Medication
|
|
|
0.500
|
|
No routine medication
|
71 (65.7)
|
27 (60)
|
|
|
Routine medication
|
37 (34.3)
|
18 (40)
|
|
Abbreviations: GOHAI, Geriatric Oral Health Assessment Index; OHRQoL, oral health-related
quality of life.
*Chi-square analysis.
As depicted in [Table 2], the means of OHIS, GOHAI, DMFT, NOP, and salivary flow rate measurement were categorized
as moderate, poor, high, ≤5, and normal, respectively. The percentage of subjects
with periodontal pockets was less than in subjects without a periodontal pocket. In
contrast, the percentage of subjects with xerostomia was more than in subjects without
xerostomia.
Table 2
Means and percentages of variable measurement (N = 153)
No.
|
Risk factors
|
Mean ± SD
|
1.
|
OH
|
2.31 ± 1.36
|
2.
|
GOHAI
|
45.5 ± 9.52
|
3.
|
DMFT
|
20.13 ± 9.45
|
4.
|
NOP
|
2.93 ± 4.03
|
5.
|
Salivary flow rate (mL/min)
|
0.26 ± 0.26
|
|
|
n
(%)
|
6.
|
Periodontal pocket
|
|
|
Yes
|
39 (25.5)
|
|
No
|
114 (74.5)
|
7.
|
Xerostomia
|
|
|
Yes
|
92 (60.13)
|
|
No
|
61 (39.87)
|
Abbreviations: DMFT, decayed, missing, and filled teeth; GOHAI, Geriatric Oral Health
Assessment Index; NOP, natural occluding pairs; OH, oral hygiene; SD, standard deviation.
The results showed that participants with NOP ≤5 have the highest percentage of 79.4%,
followed by high DMFT (75.7%) and xerostomia (67.3%) as shown in [Table 3]. Participants with low OHRQoL were found to be as much as 70.6%.
Table 3
Frequency for each risk factor related with low OHRQoL (N = 153)
|
|
Low OHRQoL
|
No.
|
Risk Factors
|
Yes n (%)
|
No n (%)
|
1.
|
Hyposalivation
|
|
|
|
Yes
|
31 (29)
|
9 (19.6)
|
|
No
|
76 (71)
|
37 (80.4)
|
2.
|
Xerostomia
|
|
|
|
Yes
|
72 (67.3)
|
20 (43.5)
|
|
No
|
35 (32.7)
|
26 (56.5)
|
3.
|
Periodontal pocket
|
|
|
|
Yes
|
26 (24.3)
|
13 (28.3)
|
|
No
|
81 (75.7)
|
33 (71.7)
|
4.
|
High DMFT
|
|
|
|
Yes
|
81 (75.7)
|
29 (63)
|
|
No
|
26 (24.3)
|
17 (37)
|
5.
|
NOP ≤ 5
|
|
|
|
Yes
|
85 (79.4)
|
27 (58.7)
|
|
No
|
22 (20.6)
|
19 (41.3)
|
6.
|
Poor OH
|
|
|
|
Yes
|
32 (29.9)
|
12 (26.1)
|
|
No
|
75 (70.1)
|
34 (73.9)
|
Abbreviations: DMFT, decayed, missing, and filled teeth; NOP, natural occluding pairs;
OH, oral hygiene; OHRQoL, oral health-related quality of life.
Bivariate analysis was conducted to determine the size of the association strength
of each risk factor with low OHRQoL. This analysis revealed that xerostomia and NOP
≤5 had a significant relationship with low OHRQoL as shown in [Table 4]. Subsequently, two risk factors (xerostomia and NOP ≤5), which had a p < 0.05, were
involved in the multivariate analysis.
Table 4
Bivariate analysis to measure the association strength among each risk factor with
low OHRQoL
No.
|
Risk Factors
|
p-Value
|
r
|
CI (95%)
|
1.
|
Hyposalivation
|
0.225
|
1.573
|
0.681–3.637
|
2.
|
Xerostomia
|
0.006*
|
2.532
|
1.255–5.108
|
3.
|
Periodontal pocket
|
0.606
|
0.846
|
0.391–1.830
|
4.
|
High DMFT
|
0.110
|
1.759
|
0.843–3.670
|
5.
|
NOP ≤5
|
0.008*
|
1.133
|
0.522–2.461
|
6.
|
Poor OH
|
0.632
|
2.723
|
1.293–5.734
|
Abbreviations: CI, confidence interval; DMFT, decayed, missing, and filled teeth;
NOP, natural occluding pairs; OH, oral hygiene; OHRQoL, oral health-related quality
of life; r, correlation coefficient.
*) p < 0.0.
The results from the multivariate analysis in [Table 5] indicated that xerostomia and NOP ≤5 were the risk factors for low OHRQoL in the
elders living in Yogyakarta. Participants with xerostomia or NOP ≤5 had 2.5 times
higher risk of having low OHRQoL.
Table 5
Multivariate analysis of xerostomia and NOP ≤5 toward low OHRQoL
|
|
|
95% CI for OR
|
Risk factors
|
Sig.
|
OR
|
Lower
|
Upper
|
Xerostomia
|
0.012
|
2.519
|
1.221
|
5.195
|
NOP ≤5
|
0.018
|
2.536
|
1.175
|
5.477
|
Abbreviations: CI, confidence interval; NOP, natural occluding pairs; OHRQoL, oral
health-related quality of life; OR, odds ratio; Sig., significance.
Discussion
[Table 1] demonstrated that only gender and occupation had significant contributions to the
proportion of the OHRQoL status. Female subjects had a more significant proportion
of poor OHRQoL status compared to male subjects. Formal worker subjects had a more
significant proportion of poor OHRQoL status compared to the other two occupations
(household worker and informal worker). Gender was also considered a factor influencing
OHRQoL. Cohen-Carneiro et al. clearly show that women are associated with a negative
perception of OHRQoL.[22] Women will be more worried, disturbed, and dissatisfied with their oral health,
even though women actually have more knowledge about oral health than men.[23] For this reason, when women are asked to rate their quality of life, they tend to
rate lower because in general their standards and expectations are higher. Their review
showed that there is a positive relationship between the level of poverty and education
with OHRQoL.[22] The poorer or the lower the education of a person, the worse the impact on OHRQoL.
What was conveyed by Cohen-Carneiro et al. is not in line with the results of this
study. Poor OHRQoL is more common in formal workers than in households and informal
workers. Formal workers usually come from people who are more educated. As it is known,
a person who is more educated tends to judge something with a more complex and careful
perception because it is based on his broader knowledge and many considerations. When
they are asked to rate their quality of life, they tend to rate very carefully or
lower.
Xerostomia or dry mouth is a subjective sensation experienced by approximately 20%
of adults.[24]
[25] The prevalence of xerostomia increases with age. Approximately 30% of the population
aged ≥65 years have experienced xerostomia.[20]
[24] The xerostomia percentage of participants with low OHRQoL was 67.3% in this study.
Xerostomia can also be accompanied with or without hyposalivation. Similarly, hyposalivation
is not always accompanied by xerostomia. The causes of xerostomia are quite varied,
ranging from the effects of uncontrolled systemic diseases, such as diabetes mellitus,
to the effect of medications, such as antihypertensive drugs, radiotherapy and chemotherapy
complications, dehydration, and certain psychological conditions (such as anxiety
and stress).[24]
[25]
[26]
The results of this study demonstrated that 90.1% of subjects experienced xerostomia,
however, only 26.1% were proven to be hyposalivation. This condition was probably
contributed by 18 subjects with diabetes mellitus and 42 subjects with hypertension,
most of whom were taking antihypertensive drugs which were xerogenic. Other xerogenic
drugs that might affect xerostomia include antidepressants, antihistamines, cytotoxics,
and bronchodilators.[18]
[26] Approximately 500 xerogenic drugs from 42 drug categories and 56 subcategories were
also found.[27] A total of 80% of the drugs prescribed by doctors have an effect on xerostomia in
the elders.[15]
[28] Therefore, assuming that the medications taken by the elders might play an important
role in the development of xerostomia or hyposalivation is reasonable.[16]
[18] Moreover, assuming that the elders involved in this study were taking other xerogenic
drugs that might affect the prevalence of xerostomia is justifiable. Participants
with xerostomia in this study might experience hyposalivation given that the prevalence
of hyposalivation in this study reached 26.1%. This prevalence is lower compared with
the meta-analysis report of hyposalivation prevalence for unstimulated methods in
elderly people (33.39%).[29] Saliva has many important roles, including its buffering capacity function, antibacterial
activity, the self-cleansing mechanism of the liquid component, and its function related
to food intake.[30]
[31]
[32]
[33] Therefore, reduced salivary flow decreases the ability of the saliva to perform
its vital functions, such as self-cleansing mechanism, antibacterial action, neutralization
of its pH in the oral cavity, and tooth remineralization.[32]
[33] By contrast, two diseases demonstrated the highest prevalence in the oral cavity,
namely, dental caries and periodontal disease, which is an infectious disease. Reduction
in salivary flow might lead to impaired abilities to improve oral hygiene and prevent
periodontal disease and dental caries.[34]
[35] This finding is proven by the high percentage of DMFT, periodontal pockets, and
poor OH among the participants in this study. Tooth loss can be the endpoint of these
diseases if left untreated. Teeth have several vital functions, such as masticatory
function, speech production, and aesthetics. These functions could not be optimally
performed in the absence of several teeth.
The various effects of xerostomia, such as poor oral hygiene, dental caries, and NOP
≤5, disturb the function and comfort of the oral cavity. The percentages of the xerostomia
effects in this study were relatively high. This finding is quite rational because
it impacted the low OHRQoL. Moreover, a previous study has shown that poor oral hygiene
leads to a low OHRQoL.[36] Another study also demonstrated the presence of a negative moderate correlation
between the occurrence of dental caries and OHRQoL among the elderly population in
Yogyakarta.[37] In their systematic review, Rijt et al. stated that OHRQol was positively correlated
with a higher number of teeth and NOP, but negatively correlated with xerostomia,
orofacial pain, and poor chewing ability.[38] Rijt et al.'s statement corroborates the results of this study which indicates that
xerostomia and a small amount of NOP are risk factors for low OHRQoL.
The assessment of xerostomia and OHRQoL in this study is subjective because it depends
on the perception of a person. Locker argued that the concept of quality of life is
elusive and abstract.[39] Intuitively, life quality is understandable but is difficult to define.[1]
[2] Perceptions of life quality can also be influenced by many factors, such as social
conditions, level of education, culture, politics, and practice, depending on the
place where the concept is applied and measured. The analysis is closely related to
values of life, which substantially vary from one person to another.[2]
[5]
[40] Petersen and Yamamoto indicated that life quality is one's perception of life considering
culture and norms based on a person's life related to the goals, expectations, standards,
and concerns over their lifetime.[41] Thus, OHRQoL is simply defined as how good is your mouth for you. OHRQoL assessment
is subjective; thus, as a reasonable risk factor for low OHRQoL rather than hyposalivation,
xerostomia assessment is also subjective. This finding was quite plausible based on
a previous study, which revealed hyposalivation as the risk factor for poor oral health
status; thus, both assessments are objective.[42] The results of this study are in accordance with the results of research by Arsyad
and Syamson stated that the elderly who experienced xerostomia had a lower OHRQoL
as measured by OHIP-14 than the elderly who did not experience xerostomia.[43] This indicates that the results of this study are still relevant to the condition
of the elderly lately. The relevance of the results of this study to recent conditions
is also supported by the percentage of poor OHRQoL in elderly subjects from the study
of Gita et al. (66.7%).[44] Gita et al.'s result is not much different from the percentage of poor OHRQoL in
this study (70.1%). The OHRQoL measurement instrument used is the same, namely GOHAI.
Considering the effects of xerostomia and NOP ≤5, the participants will reasonably
have low OHRQoL due to disturbances in some aspects of function, pain/discomfort,
psychological conditions, and disrupted social well-being. One way to increase OHRQoL
is by wearing dentures. This suggestion is based on previous research which proved
that the use of dentures in elderly patients who lost their teeth partially or completely
can increase OHRQoL, reduce anxiety, and feel more saliva secretion.[45] The lack of salivary secretion might also cause a variety of disorders in the oral
cavity, such as poor oral hygiene, dental caries, periodontal disease, and burning
sensation, which will eventually induce pain. Disruption of mastication perceived
by the individuals from tooth loss might increase the possibility of an individual
withdrawing from social interactions. This phenomenon will affect the psychological
condition of a person that can impact OHRQoL.
Saliva forms food boluses to ease the swallowing action; it will also bring chewed
food to the taste buds of the tongue papillae to help a person in tasting the food.[33] Xerostomia alters the quantity and/or quality of saliva, which may cause difficulties
in masticating, swallowing, speaking, and altered taste.[30]
[31]
[32]
[33]
[34]
[35] These conditions can affect OHRQoL negatively. This study showed that 70.6% of elders
had low OHRQoL. The low OHRQoL of the majority of elders in this study was partly
due to the low oral health awareness among Indonesians. Most Indonesians still believe
that general health is more important than oral health.
A cross-sectional design was used in this study. Therefore, the limitation of this
study lies in its failure to explain the causal relationship between xerostomia or
NOP ≤ 5 and low OHRQoL. Another weakness of this research i.e. there is no assessment
regarding the participants' cognitive, communication, and listening abilities beforehand.
The inability of participants was only discovered during the study, thus causing the
loss of participants. Further research must be performed with a sophisticated study
design and sampling method to assure the representativeness of the sample of the population
of elders living in Yogyakarta. Developing a simple OHRQoL assessment tool originating
from Indonesia is necessary to facilitate its adjustment to the context of Indonesian
people and its understanding by the elderly people at all levels of education, without
neglecting the aspect of representativeness. According to Rai et al., to date there
are no studies have been conducted to reveal oral conditions for low OHRQoL in Indonesia
or worldwide.[46] This study will be a starting point and reference for further research so that we
will get more complete data on oral conditions as risk factors for low OHRQoL. Those
data are very important as a reference in doing better oral management for elderly
patients so that they can improve their quality of life. These are the advantages
and strengths of this study.
Conclusions
Xerostomia and NOP ≤5 are the main risk factors that contribute to the occurrence
of low OHRQoL in the elders living in Yogyakarta. Elders who suffer from xerostomia
or NOP ≤5 have 2.5 times higher risks of experiencing low OHRQoL.