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DOI: 10.1055/s-0042-1746372
Long term Weight Loss in a Primary Care-Anchored Human eHealth Lifestyle Coaching Program in Denmark: A Randomized Controlled Trial
Background Long-term weight loss among subjects with obesity can reduce the risk, and progression of noncommunicable diseases (NCDs) such as cardiovascular, respiratory disease and type 2 diabetes (T2D). Unfortunately, long-term weight loss has been historically difficult for patients with obesity and T2D to achieve and maintain. Observational studies suggest that digital coaching can lead to long-term weight loss and potentially reduce the risk of developing NCDs.
Objective To assess whether an eHealth lifestyle coaching program (Liva) for motivated subjects with obesity with or without T2D leads to significant weight loss compared to usual care.
Methods In an open, randomized controlled trial, 340 subjects with obesity with or without T2D were enrolled from March 2018 to March 2019 and randomized to the intervention (200) and control (140) groups.
Results At 12 months, data were assessed for 200 patients, 127/198 in the intervention group and 73/140 in the control group. The mean reductions in body weight (P=0.01) and BMI (P=0.00) were significantly higher in the intervention group (–4.61 kg (95% CI, -5.7; -3,4) and -1.5 kg/m2 (95% CI, -1.9; -1.2)) compared to the control group (-1.4 kg (95% CI, -2.6; -0.1) and -0.5 kg/m2 (95% CI, -0.9; -0.1)). Changes in HbA1c was significantly reduced in both groups, but not when the two group were compared. Blood pressure and lipid profile were not statistically significant.
Conclusion Compared to usual care, digital lifestyle coaching can induce significant weight loss in obese subjects with or without T2D.
Brandt CJ, Christensen JR, Lauridsen JT, Nielsen JB, Sondergaard J, Sortso C. Evaluation of the clinical and economic effects of a primary care anchored, collaborative, electronic health lifestyle coaching program in Denmark: protocol for a two-year randomized controlled trial. JMIR Res Protoc 2020;9(6):e19172.
Komkova A, Brandt CJ, Hansen Pedersen D, Emneus M, Sortso C. Electronic health lifestyle coaching among diabetes patients in a real-life municipality setting: observational study. JMIR Diabetes 2019;4(1):e12140.
Conflict of Interest
CJB owns stock in LIVA Healthcare A/S, the company that developed parts of the technical platform and hosted some of it during the study. CJB works at the Research Unit for General Practice at University of Southern Denmark. CS is an employee of LIVA Healthcare A/S. JS, JBN, JRC, and JTL have no financial interests in LIVA Healthcare A/S or any other aspects of this study.
Publication History
Article published online:
26 May 2022
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