AN EVALUATION OF A NOVEL BOWEL PREPARATION REGIMEN AND ITS EFFECT ON THE UTILITY OF COLON CAPSULE ENDOSCOPY

Aims To evaluate the efficacy of a novel bowel preparation and booster regimen for patients undergoing colon capsule endoscopy (CCE).

Methods This was a prospective audit carried out between 12/07/2021 and 29/11/2021. Symptomatic patients (those referred with lower gastrointestinal symptoms) undergoing CCE in NHS Highland trialled a new bowel preparation and booster regimen for their procedure ([Table 1]). We recorded the completeness of procedure (visualisation of the whole colon and rectum), bowel preparation adequacy, if the test was successful (complete with adequate bowel preparation) and if a further test was required following CCE. We also noted the reason for further test (either due to CCE findings or inadequate CCE.

Table 1

Day – 1	1L Moviprep solution
	1L Moviprep solution
Day of procedure	Booster 1 – 30ml of Phosphosoda and 50ml Gastrografin
	Booster 2 – 15ml of Phosphosoda and 50ml Gastrografin

Results 183 patients were included in this audit. The median age was 61 years and 114/183 (62%) were female. 130/183 (71%) patients had a complete test, 157/183 (86%) had adequate bowel preparation and 118/183 (64%) had a successful test. 76/183 (42%) of patients required no further test following CCE, 46/183 (25%) required a colonoscopy, 55/183 (30%) required a flexible sigmoidoscopy and 6/183 (3%) required a CT colonogram. 41/46 (89%) colonoscopy were required due to CCE findings, and 5/46 (11%) colonoscopy were required due to an inadequate test. 28/55 (51%) and 27/55 (49%) flexible sigmoidoscopy were required due to CCE findings and an inadequate test, respectively.

Conclusions We found the rate of adequate bowel preparation using this novel regimen comparable to colonoscopy. However, further work is needed to improve the completion rate which will reduce the need for flexible sigmoidoscopy following CCE.

 

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Publication History

Article published online:
14 April 2022