Endoscopy 2016; 48(06): v16
DOI: 10.1055/s-0042-106595
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Publication Date:
30 May 2016 (online)

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In vivo real-time assessment of colorectal polyp histology using an optical biopsy forceps system based on laser-induced fluorescence spectroscopyEndoscopy 2016; 48(06): 557-562
DOI: 10.1055/s-0042-102251

Timo Rath et al. In vivo real-time assessment of colorectal polyp histology using an optical biopsy forceps system based on laser-induced fluorescence spectroscopy

This feasibility study examines a novel laser-induced fluorescence spectroscopy system, integrated into a biopsy forceps, for real-time automated prediction of the histology of diminutive polyps. The study, including 137 polyps (115 of them hyperplastic), showed good test characteristics with an accuracy of 84.7% and a negative predictive value for distal polyps of 100% (68 polyps in 19 patients).


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