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DOI: 10.1055/s-0041-1740856
Is There a Significant Difference in the Incidence Rate of Osteoporotic Compression Fractures after Vertebroplasty as Compared with the following Conservative Management?
Background: Vertebral osteoporotic fractures are a major cause of morbidity and disability in the elderly population. This study sought to compare the incidence of new vertebral fractures in patients treated by vertebroplasty with that of those managed conservatively, while also assessing the potential risk factors contributing to the occurrence of these fractures
Materials and Methods: The details of a total of 121 eligible patients with radiologically proven osteoporotic vertebral fractures were retrieved from our archive between January 2010 and September 2019 and allocated based on the treatment method to percutaneous vertebroplasty (n = 60) or nonsurgical treatment (n = 61).
Results: The difference in the incidence of new fractures was statistically significant (p = 0.001), with rates of 70% (n = 32) in the vertebroplasty patients and 30% (n = 14) in the conservatively treated cases reported at a median follow-up time point of approximately 4 months. The presence of liver disease, a history of transplantation, the use of steroids, a low bone mineral density score, and a higher number of fractures on baseline imaging were associated with a greater risk of subsequent vertebral fractures.
Conclusion: The incidence of acute fractures after percutaneous vertebroplasty is higher than that among patients treated conservatively. Decision-making regarding the adoption of this intervention approach should be tailored to individual cases based on standard appropriateness criteria and while taking into consideration the risk factors leading to a greater risk of subsequent vertebral fractures such as a higher number of fractures at baseline imaging, low bone mineral density score, patient comorbidities, and steroid use.
No conflict of interest has been declared by the author(s).
Publication History
Article published online:
14 December 2021
© 2021. The Pan Arab Interventional Radiology Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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