Open Access
CC BY-NC-ND 4.0 · The Arab Journal of Interventional Radiology 2021; 5(S 01): S1-S26
DOI: 10.1055/s-0041-1740837
Presentation Abstracts

To Study Role of Intra-arterial Chemotherapy in Treatment of Intraocular Retinoblastoma

Authors

  • Mohammad Z. Mohammad Zakir

    1   Apollo Hospital, Chennai, India

  • Pritam Chatterjee

    1   Apollo Hospital, Chennai, India

  • R. Ravikumar

    1   Apollo Hospital, Chennai, India
Further Information
Also available at
 
 

Background: This study aimed to study the various approach and technical aspects with treatment outcome in superselective intra-arterial chemotherapy for intraocular retinoblastoma

Materials and Methods: Our study was a prospective study over a period of 3 years which included 165 patients suffering from various stages of retinoblastoma. We used superselective ostium catheterization for intra-arterial chemotherapy. Most commonly used approach was opthlamic artery; however, in some cases, middle meningeal artery approach was used.

Results: Among 165 patients, there was complete regression of the tumor in 38 patients. The total radiation dose was 3 to 8 mGy, average procedural time was <10 minutes. Total contrast usage <10 mL. Intra-arterial chemotherapy forms a main stay in treatment of retinoblastoma and helps in globe salvage further decreasing the morbidity. Post intra-arterial chemotherapy, there was decrease in tumor counts, vitreal seeding, etc. No major local/vascular complications were seen. Transient pancytopenia was seen in few of the cases.

Conclusion: Intra-arterial chemotherapy is a minimally invasive and safe technique for salvaging the eye in cases of retinoblastoma. Intra-arterial chemotherapy forms the mainstay in treatment of ocular retinoblastoma


No conflict of interest has been declared by the author(s).

Publication History

Article published online:
14 December 2021

© 2021. The Pan Arab Interventional Radiology Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India