Pleurotus is an edible mushroom and represents a well-known genus of basidiomycetes being the
third most consumed on a global scale besides to presents several biological activities.
This genus is described by presence of steroids, fatty acids and polysaccharides.
In addition, Pleurotus has become increasingly appealing as functional foods, known as nutraceuticals, due
to their health benefits. Dereplication techniques aided by high resolution mass spectrometry
and Global Natural Products Social Molecular Network (GNPS) were used to analyze the
chemical composition of methanolic extracts of six Pleurotus species (P. sapidus, P. ostreaus, P. ostreaus var. Florida, P. djamor, P. citrinopileatus and P. pulmonarius). The used approach pointed towards different molecular families including the annotation
of 8 essential fatty
acids and 7 steroids, being 6 of them suggested according to the molecular network
correlated nodes. This work shows an approach of dereplication for extracts as a relatively
rapid tool for characterization of fungi species and determined its nutraceutical
value [1]
[2]
[3].
