Dereplication of extracts from nutraceutical mushrooms Pleurotus using molecular network approach

Pleurotus is an edible mushroom and represents a well-known genus of basidiomycetes being the third most consumed on a global scale besides to presents several biological activities. This genus is described by presence of steroids, fatty acids and polysaccharides. In addition, Pleurotus has become increasingly appealing as functional foods, known as nutraceuticals, due to their health benefits. Dereplication techniques aided by high resolution mass spectrometry and Global Natural Products Social Molecular Network (GNPS) were used to analyze the chemical composition of methanolic extracts of six Pleurotus species (P. sapidus, P. ostreaus, P. ostreaus var. Florida, P. djamor, P. citrinopileatus and P. pulmonarius). The used approach pointed towards different molecular families including the annotation of 8 essential fatty

acids and 7 steroids, being 6 of them suggested according to the molecular network correlated nodes. This work shows an approach of dereplication for extracts as a relatively rapid tool for characterization of fungi species and determined its nutraceutical value [1] [2] [3].

 

Scroll to top

The authors declare no conflict of interest.

• References

• 1 Corrêa R.C.G.. et al. (2016). Trends in Food Science and Technology, 50, 103–117
• 2 Balaji P.. Madhanraj et al. (2020). Saudi Journal of Biological Sciences, 27(3), 913–924
• 3 Aron A.T., Gentry E.C., Mcphail K.L. (2020). Nat Protoc, 15, 1954–1991

Publication History

Article published online:
13 December 2021