Planta Med 2021; 87(15): 1248-1249
DOI: 10.1055/s-0041-1736777
Abstracts
3. Short Lectures

The LOTUS initiative for knowledge sharing in Natural Products research

Adriano Rutz
1   University of Geneva, Institute of Pharmaceutical Sciences of Western Switzerland, Geneva
,
Maria Sorokina
2   Friedrich-Schiller-University Jena, Institute for Inorganic and Analytical Chemistry, Jena
,
Jakub Galgonek
3   Institute of Organic Chemistry and Biochemistry of the CAS, Prague
,
Daniel Mietchen
4   University of Virginia, School of Data Science, Charlottesville
,
Egon Willighagen
5   Maastricht University, Dept of Bioinformatics-BiGCaT, Maastricht
,
Arnaud Gaudry
1   University of Geneva, Institute of Pharmaceutical Sciences of Western Switzerland, Geneva
,
James G. Graham
6   University of Illinois at Chicago, Department of Pharmaceutical Sciences, Chicago
,
Ralf Stephan
7   Ontario Institute for Cancer Research, Toronto
,
Roderic Page
8   University of Glasgow, BAHCM, MVLS, Glasgow
,
Jiří Vondrášek
3   Institute of Organic Chemistry and Biochemistry of the CAS, Prague
,
Christoph Steinbeck
2   Friedrich-Schiller-University Jena, Institute for Inorganic and Analytical Chemistry, Jena
,
Guido F. Pauli
6   University of Illinois at Chicago, Department of Pharmaceutical Sciences, Chicago
,
Jean-Luc Wolfender
1   University of Geneva, Institute of Pharmaceutical Sciences of Western Switzerland, Geneva
,
Jonathan Bisson
6   University of Illinois at Chicago, Department of Pharmaceutical Sciences, Chicago
,
Pierre-Marie Allard
9   University of Fribourg, Department of Biology, Fribourg;
› Author Affiliations

CRSII5_189921, CRC1127, LM2018131, G-2019-11458, U41 AT008706 and AT000155
› Further Information
Also available ateRef
 
 

With the recent explosion of information, Natural Products (NP) research critically needs efficient ways to access and share knowledge, also to save precious knowledge being lost [1]. The reporting and sharing of NP occurrences in biological organisms are relevant to numerous scientific fields ranging from drug discovery to chemical ecology or chemotaxonomy.

Through the LOTUS initiative, we aim to offer better knowledge sharing in NP research. We established a data harmonization, curation, and validation pipeline to gather and appropriately document structure-organism pairs. These pairs are then shared through the Wikidata platform. Wikidata is particularly indicated for the sharing of knowledge in life sciences as demonstrated in [2]. We made 700,000+referenced structure-organism pairs available on Wikidata. As an example, it is, now possible to retrieve biological organisms containing chemical compounds described as anti-infective (https://w.wiki/vo9). This offers exciting perspectives, linking information gained over different, sometimes disconnected, fields of investigation.


 

The authors declare no competing interest.


Publication History

Article published online:
13 December 2021

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