One-Year Outcomes of the Paclitaxel-Eluting Stent for TASC C and D Femoropopliteal Lesions in Real World

Objectives: The aim of this study was to assess the 1-year outcomes of the paclitaxel-eluting stent (PES) for TASC C and D femoropopliteal lesions. Methods: This study is a single-center, retrospective observational study of PES for peripheral arterial disease. From February 2017 and May 2018, the patients who underwent PES (two types; Zilver PTX, COOK Medical and Eluvia, Boston Scientific) for TASC C/D femoropopliteal lesions were included. Primary patency, target lesion revascularization, and event-free survival up to 12 months after the procedure were evaluated. Results: A total of 34 patients (37 limbs) were included (30 males and 4 females; mean age: 71.9 ± 9.1 years; range: 53–90 years). Twenty-five limbs (68%) were TASC D lesions and 12 limbs (32%) were TASC C lesions. The mean lesion length was 24.6 ± 6.6 cm (range, 9–46 cm). Seventeen lesions (46%) had more than a moderate calcific burden. The mean number of stents was 2.5 ± 0.7 (1–3), covering 24.3 ± 7.9 cm (range: 6–35 cm). A total of 23 Zilver PTX stents and 14 Eluvia stents were used. The Kaplan–Meier estimate of 1-year primary patency (PP) and freedom from target lesion revascularization (fTLR) were 78% and 88% (Zilver PTX, 81% and 76%; Eluvia, 91% and 100%). Event-free survival was 84% in two patients. Major adverse events requiring treatment occurred in two patients (2/34, 5.8%), which were acute thrombotic occlusions. Conclusion: The 1-year outcome of PES for TASC C/D femoropopliteal lesion in the real world showed promising PP and fTLR rates, which are not significantly different from previous data.

Publication History

Article published online:
26 April 2021