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Journal of Pediatric Neurology 2022; 20(06): 365-372
DOI: 10.1055/s-0041-1726088
Review Article

Cognitive Deficits in Pediatric Craniopharyngioma: An Updated Review

Abdulrahman Al-Mirza 
1   College of Medicine, Sultan Qaboos University, Sultanate of Oman-Muscat, Al-khoudh
,
Omar Al-Taei
1   College of Medicine, Sultan Qaboos University, Sultanate of Oman-Muscat, Al-khoudh
,
Tariq Al-Saadi
2   Department of Neurology and Neurosurgery, Montreal Neurological Institute, Faculty of Medicine, McGill University, QC, Canada
3   Department of Neurosurgery, Khoula Hospital, Muscat, Sultanate of Oman
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Abstract

Craniopharyngiomas (CP) are brain tumors that often occur in children and adolescent that results in many neurological and endocrinological disorders. The aim of this systematic review is to provide updated version of studies used to formalize standard tests used for cognitive impairment in pediatric patients with craniopharyngioma. A systematic review was conducted in PubMed, EBSCO, ProQuest, Science Direct, Wiley Online, and Springer to identify studies assessing cognitive impairment in pediatric patients with craniopharyngioma. Academic and learning dysfunctions were reported in seven studies among 41 of 178 patients (23%). Visual–spatial deficits were reported in six studies. Speech and verbal dysfunctions were reported in three studies. Memory deficits were reported in eight studies among 61 of 197 patients (31%). Motor dysfunctions were reported in five studies. Sleep related issues were reported in four studies among 33 of 70 patients (47.1%). Patients with treated pediatric CP demonstrate a high incidence of neurological deficits including cognitive dysfunctions. Academic and learning dysfunctions, visual–spatial deficits, speech and verbal dysfunctions, memory deficits, and sleep-related issues were the most commonly reported cognitive deficits in the present study.

Keywords

craniopharyngioma - pediatric - cognitive functions - deficit


Publication History

Received: 07 December 2020

Accepted: 21 January 2021

Article published online:
16 March 2021

© 2021. Thieme. All rights reserved.

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