Seminars in Reproductive Medicine, Inhaltsverzeichnis Semin Reprod Med 2020; 38(04/05): 237-246DOI: 10.1055/s-0040-1722317 Review Article Prevalence and Risk Factors of Premature Ovarian Insufficiency/Early Menopause Rinky Giri 1 Department of Endocrinology, Monash Health, Clayton, Victoria, Australia , Amanda J. Vincent 1 Department of Endocrinology, Monash Health, Clayton, Victoria, Australia 2 Monash Centre for Health Research and Implementation (MCHRI), School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia › InstitutsangabenArtikel empfehlen Abstract Artikel einzeln kaufen Abstract Premature ovarian insufficiency (POI) and early menopause, defined as loss of ovarian activity prior to 40 years or menopause between the ages of 40 and 45 years, respectively, is associated with significant adverse health impacts. Recent data indicate that the prevalence of POI and early menopause is greater than was previously thought, affecting more than 10% of women. Biopsychosocial risk factors including genetic, autoimmune, reproductive, lifestyle, early-life, social/environmental, and iatrogenic have been associated with POI/early menopause or earlier age at menopause. However, establishing a causal role and the underlying mechanisms remains elusive. Understanding and clarification of these risk factors will facilitate prevention and risk minimization strategies to optimize women's health. Keywords Keywordspremature ovarian insufficiency - early menopause - risk factors - prevalence Volltext Referenzen References 1 Webber L, Davies M, Anderson R. et al; European Society for Human Reproduction and Embryology (ESHRE) Guideline Group on POI. ESHRE Guideline: management of women with premature ovarian insufficiency. Hum Reprod 2016; 31 (05) 926-937 2 InterLACE Study Team. 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