J Pediatr Intensive Care 2022; 11(01): 019-025
DOI: 10.1055/s-0040-1721657
Original Article

Comparison of Ketamine and Propofol-Based Regimens for Deep Sedation in Children Undergoing Esophagogastroduodenoscopy

Olugbenga Akingbola
1   Division of Pediatric Critical Care, Department of Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana, United States
,
Sudesh K. Srivastav
2   Department of Biostatistics and Data Science, Tulane University, New Orleans, Louisiana, United States
,
3   Tulane University School of Medicine, New Orleans, Louisiana, United States
,
4   Baylor Scott and White McLane Children's Medical Center, Temple, Texas, United States
,
Edwin M. Frieberg
1   Division of Pediatric Critical Care, Department of Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana, United States
,
Amy Thibodeaux
5   Ochsner Health System, New Orleans, Louisiana, United States
› Institutsangaben
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Abstract

We retrospectively reviewed the charts of 180 children sedated for esophagogastroduodenoscopy (EGD) with ketamine or propofol-based regimens at our institution. Pre-EGD diagnoses and American Society of Anesthesiology physical status were similar in all subjects. Onset of action and recovery time for both regimens were not statistically significant (p > 0.05). Mean onset of sedation for all patients was 3.85 ± 3.04 minutes, mean Aldrete score was 6.31 ± 0.61, and mean recovery time was 51.85 ± 31.78 minutes (p > 0.05). Sedation-related adverse events observed include apnea, hypoxemia, bradycardia, hypotension, laryngospasm, skin rash, and wheezing. Deep sedation for pediatric EGD is safe if patients are carefully screened and properly monitored.

Note

This study was presented as an electronic abstract at the 2019 annual meeting of the American Society of Anesthesiology.




Publikationsverlauf

Eingereicht: 31. Mai 2020

Angenommen: 19. September 2020

Artikel online veröffentlicht:
23. November 2020

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