Therapy-Related Imaging Findings in Patients with Sarcoma

Johan L. Bloem; Dennis Vriens; Augustinus D.G. Krol; Murat Özdemir; Michiel A.J. van de Sande; Hans Gelderblom; Judith V.M.G. Bovee; Jos A. van der Hage; Iris M. Noebauer-Huhmann

doi:10.1055/s-0040-1721097

Seminars in Musculoskeletal Radiology, Table of Contents

Semin Musculoskelet Radiol 2020; 24(06): 676-691
DOI: 10.1055/s-0040-1721097

Review Article

Therapy-Related Imaging Findings in Patients with Sarcoma

Johan L. Bloem

¹Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

,

Dennis Vriens

¹Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

,

Augustinus D.G. Krol

²Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands

,

Murat Özdemir

¹Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

,

Michiel A.J. van de Sande

³Department of Orthopedics, Leiden University Medical Center, Leiden, The Netherlands

,

Hans Gelderblom

⁴Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands

,

Judith V.M.G. Bovee

⁵Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands

,

Jos A. van der Hage

⁶Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands

,

Iris M. Noebauer-Huhmann

⁷Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria

› Author Affiliations

Abstract

Knowledge of imaging findings related to therapy administered to patients with sarcoma is pivotal in selecting appropriate care for these patients. Imaging studies are performed as surveillance in asymptomatic patients or because symptoms, including anxiety, develop. In addition to detection of recurrent disease and assessment of response to therapy, diagnosis of conditions related to therapy that may or may not need treatment has a marked positive impact on quality of life. The purpose of this review is to assist radiologists, nuclear physicians, and others clinicians involved in the diagnosis and treatment of these patients in recognizing imaging findings related to therapy and not to activity of the previously treated sarcoma. Imaging findings are time dependent and often specific in relation to therapy given.

Keywords

sarcoma - surgery - radiotherapy - oncology - radiology

Full Text

References

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