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Thromb Haemost 2021; 121(02): 192-205
DOI: 10.1055/s-0040-1716530
Cellular Haemostasis and Platelets

Ibrutinib Suppresses Early Megakaryopoiesis but Enhances Proplatelet Formation

Jiansong Huang*
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Shujuan Huang*
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Zhixin Ma
4   Clinical Prenatal Diagnosis Center, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Xiangjie Lin
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Xia Li
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Xin Huang
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Jinghan Wang
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Wenle Ye
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Yang Li
5   Department of Obstetrics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Daqiang He
6   Department of Laboratory Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Min Yang
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Jiajia Pan
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Qing Ling
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Fenglin Li
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Shihui Mao
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Huafeng Wang
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Yungui Wang
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
,
Jie Jin
1   Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
2   Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Hangzhou, Zhejiang Province, China
3   Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
› Author Affiliations