Zielsetzung Implant-based or expander-supported breast reconstruction is an established surgical
method. In a prospective, single-arm, multi-center study the patient reported outcome
(PRO) after breast reconstruction with a synthetic surgical mesh was investigated.
The focus of this study was the analysis of patient reported outcome 12 months after
breast reconstruction.
Materialien und Methoden Primary or secondary implant-based breast reconstruction with support of a titanium-coated
polypropylene mesh (TiLOOP® Bra) was performed in 269 patients in the course of the PRO-BRA study. Patient reported
outcome 12 months after breast reconstruction was evaluated using the established
Breast-Q questionnaire. Cosmetic outcome was evaluated by two independent experts.
Ergebnisse The Breast-Q and 12 months FU were completed by 210 women. Patients without AE had
a significantly higher Breast-Q score for “sexual well-being”; “psychosocial well-being”
was negatively influenced by prior therapies, and patients > 40 years had significantly
lower scores at 12 months FU for “ satisfaction with breasts (SwB)” while the opposite
was true for patients ≤ 40 years. The BMI only influenced PRO preoperatively. Unilateral
surgery resulted in reduced “satisfaction with breast”; a higher UICC stadium (II-IV)
resulted in worse “SwB”. Radiotherapy negatively influenced “SwB”. The cosmetic evaluation
showed a significant difference in the evaluation by the patients and experts with
the patients’ assessment being worse.
Zusammenfassung Our trial showed that two years after implant-based breast reconstruction with support
of TiLOOP® Bra PRO is influenced by different factors. This information can be used to improve
the decision-making process for women who chose implant-based breast reconstruction.
