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J Pediatr Intensive Care 2020; 09(04): 277-883
DOI: 10.1055/s-0040-1712920
Original Article

Preadmission Diet and Zip Code Influences the Pediatric Critical Care Clinical Course for Infants with Severe Respiratory Illness (N = 187)

Mara L. Leimanis Laurens 
1   Pediatric Critical Care Unit, Helen DeVos Children's Hospital, Grand Rapids, Michigan, United States
2   Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States
,
Amina M. Jaji 
2   Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States
3   Spectrum Health, Grand Rapids, Michigan, United States
,
Jessica Montgomery
2   Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States
,
Jennifer Jess
2   Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States
,
Karen Ferguson
3   Spectrum Health, Grand Rapids, Michigan, United States
,
Jessica Parker
3   Spectrum Health, Grand Rapids, Michigan, United States
,
Dominic Sanfilippo
1   Pediatric Critical Care Unit, Helen DeVos Children's Hospital, Grand Rapids, Michigan, United States
2   Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States
,
Surender Rajasekaran
1   Pediatric Critical Care Unit, Helen DeVos Children's Hospital, Grand Rapids, Michigan, United States
2   Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States
› Author Affiliations Funding M.L. and S.R. are recipients of the Spectrum Health Office of Research grant (#RI0027-19), researching dietary influences in the infant population.
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Abstract

We examined preadmission diet and zip code in infants with severe respiratory illness in the pediatric critical care unit. Patients aged 0 to 5 months admitted to the Helen DeVos Children's Hospital from January 2011 to May 2017 (N = 187), as exclusively formula, exclusively breastfed or mixed diet were included. Formula-fed infants (n = 88; 47%) clustered to zip codes with lower median incomes (<0.005), used public insurance as their payer type (p < 0.005), and were prescribed more ranitidine (p < 0.05) on admission.

Keywords

diet - pediatric critical care unit - severe respiratory illness - median household income - zip code

Supplementary Material



Publication History

Received: 24 October 2019

Accepted: 22 April 2020

Article published online:
28 May 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Stuttgart · New York

 

  • References

  • 1 Ralston SL, Lieberthal AS, Meissner HC. et al; American Academy of Pediatrics. Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis. Pediatrics 2014; 134 (05) e1474-e1502
    CrossrefPubMedGoogle Scholar
  • 2 Horta BL, Victora CG. Respiratory infection. In: Short Term Effects of Breastfeeding: a Systematic Review on the Benefits of Breastfeeding on Diarrhoea and Pneumonia Mortality. Geneval, Switzerland: World Health Organization; 2013: 30-33
    Google Scholar
  • 3 Hall CB, Weinberg GA, Iwane MK. et al. The burden of respiratory syncytial virus infection in young children. N Engl J Med 2009; 360 (06) 588-598
    CrossrefPubMedGoogle Scholar
  • 4 WHO. Burden of disease project. In: Organization WH. ed. Geneva, Switzerland: World Health Organization; 2005
    Google Scholar
  • 5 Verduci E, Martelli A, Miniello VL. et al. Nutrition in the first 1000 days and respiratory health: a descriptive review of the last five years' literature. Allergol Immunopathol (Madr) 2017; 45 (04) 405-413
    CrossrefPubMedGoogle Scholar
  • 6 Bachrach VR, Schwarz E, Bachrach LR. Breastfeeding and the risk of hospitalization for respiratory disease in infancy: a meta-analysis. Arch Pediatr Adolesc Med 2003; 157 (03) 237-243
    CrossrefPubMedGoogle Scholar
  • 7 Andreas NJ, Kampmann B, Mehring Le-Doare K. Human breast milk: a review on its composition and bioactivity. Early Hum Dev 2015; 91 (11) 629-635
    CrossrefPubMedGoogle Scholar
  • 8 Tomicić S, Johansson G, Voor T, Björkstén B, Böttcher MF, Jenmalm MC. Breast milk cytokine and IgA composition differ in Estonian and Swedish mothers-relationship to microbial pressure and infant allergy. Pediatr Res 2010; 68 (04) 330-334
    CrossrefPubMedGoogle Scholar
  • 9 Garofalo R. Cytokines in human milk. J Pediatr 2010; 156 (02) S36-S40
    CrossrefPubMedGoogle Scholar
  • 10 Ruiz L, Espinosa-Martos I, García-Carral C. et al. What's normal? immune profiling of human milk from healthy women living in different geographical and socioeconomic settings. Front Immunol 2017; 8: 696
    CrossrefPubMedGoogle Scholar
  • 11 Belanoff CM, McManus BM, Carle AC, McCormick MC, Subramanian SV. Racial/ethnic variation in breastfeeding across the US: a multilevel analysis from the National Survey of Children's Health, 2007. Matern Child Health J 2012; 16 (Suppl. 01) S14-S26
    CrossrefPubMedGoogle Scholar
  • 12 Howie PW, Forsyth JS, Ogston SA, Clark A, Florey CD. Protective effect of breast feeding against infection. BMJ 1990; 300 (6716): 11-16
    CrossrefPubMedGoogle Scholar
  • 13 Persad MD, Mensinger JL. Maternal breastfeeding attitudes: association with breastfeeding intent and socio-demographics among urban primiparas. J Community Health 2008; 33 (02) 53-60
    CrossrefPubMedGoogle Scholar
  • 14 Romaine A, Clark RH, Davis BR. et al. Predictors of prolonged breast milk provision to very low birth weight infants. J Pediatr 2018; 202: 23-30.e1
    CrossrefPubMedGoogle Scholar
  • 15 Santiago J, Mansbach JM, Chou SC. et al. Racial/ethnic differences in the presentation and management of severe bronchiolitis. J Hosp Med 2014; 9 (09) 565-572
    CrossrefPubMedGoogle Scholar
  • 16 Lacroix J, Infante-Rivard C, Gauthier M, Rousseau E, van Doesburg N. Upper gastrointestinal tract bleeding acquired in a pediatric intensive care unit: prophylaxis trial with cimetidine. J Pediatr 1986; 108 (06) 1015-1018
    CrossrefPubMedGoogle Scholar
  • 17 Leteurtre S, Martinot A, Duhamel A. et al. Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study. Lancet 2003; 362 (9379): 192-197
    CrossrefPubMedGoogle Scholar
  • 18 Pollack MM, Patel KM, Ruttimann UE. PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med 1996; 24 (05) 743-752
    CrossrefPubMedGoogle Scholar
  • 19 Vereen S, Gebretsadik T, Hartert TV. et al. Association between breast-feeding and severity of acute viral respiratory tract infection. Pediatr Infect Dis J 2014; 33 (09) 986-988
    CrossrefPubMedGoogle Scholar
  • 20 Berger I, Weintraub V, Dollberg S, Kopolovitz R, Mandel D. Energy expenditure for breastfeeding and bottle-feeding preterm infants. Pediatrics 2009; 124 (06) e1149-e1152
    CrossrefPubMedGoogle Scholar
  • 21 Heilbronner C, Roy E, Hadchouel A. et al. Breastfeeding disruption during hospitalisation for bronchiolitis in children: a telephone survey. BMJ Paediatr Open 2017; 1 (01) e000158
    CrossrefPubMedGoogle Scholar
  • 22 Gimeno-Alcañiz JV, Collado MC. Impact of human milk on the transcriptomic response of fetal intestinal epithelial cells reveals expression changes of immune-related genes. Food Funct 2019; 10 (01) 140-150
    CrossrefPubMedGoogle Scholar
  • 23 Wen X, Kong KL, Eiden RD, Sharma NN, Xie C. Sociodemographic differences and infant dietary patterns. Pediatrics 2014; 134 (05) e1387-e1398
    CrossrefPubMedGoogle Scholar
  • 24 Franklin JA, Anderson EJ, Wu X, Ambrose CS, Simões EA. Insurance status and the risk of severe respiratory syncytial virus disease in United States Preterm Infants Born at 32-35 Weeks Gestational Age. Open Forum Infect Dis 2016; 3 (03) ofw163
    CrossrefPubMedGoogle Scholar
  • 25 Foley D, Best E, Reid N, Berry MMJ. Respiratory health inequality starts early: The impact of social determinants on the aetiology and severity of bronchiolitis in infancy. J Paediatr Child Health 2019; 55 (05) 528-532
    CrossrefPubMedGoogle Scholar
  • 26 Cardoso MR, Cousens SN, de Góes Siqueira LF, Alves FM, D'Angelo LA. Crowding: risk factor or protective factor for lower respiratory disease in young children?. BMC Public Health 2004; 4: 19
    CrossrefPubMedGoogle Scholar
  • 27 Mangili G, Garzoli E. Feeding of preterm infants and fortification of breast milk. Pediatr Med Chir 2017; 39 (02) 158
    CrossrefPubMedGoogle Scholar
  • 28 Valentine CJ, Hurst NM, Schanler RJ. Hindmilk improves weight gain in low-birth-weight infants fed human milk. J Pediatr Gastroenterol Nutr 1994; 18 (04) 474-477
    CrossrefPubMedGoogle Scholar
  • 29 Collaborative Dexamethasone Trial Group. Dexamethasone therapy in neonatal chronic lung disease: an international placebo-controlled trial. Pediatrics 1991; 88 (03) 421-427
    PubMedGoogle Scholar
  • 30 Gale SM, Read LC, George-Nascimento C, Wallace JC, Ballard FJ. Is dietary epidermal growth factor absorbed by premature human infants?. Biol Neonate 1989; 55 (02) 104-110
    CrossrefPubMedGoogle Scholar
  • 31 Ouellet J, Bailey D, Samson ME. Current opinions on stress-related mucosal disease prevention in Canadian Pediatric Intensive Care Units. J Pediatr Pharmacol Ther 2015; 20 (04) 299-308
    PubMedGoogle Scholar
  • 32 Santana RNS, Santos VS, Ribeiro-Júnior RF. et al. Use of ranitidine is associated with infections in newborns hospitalized in a neonatal intensive care unit: a cohort study. BMC Infect Dis 2017; 17 (01) 375
    CrossrefPubMedGoogle Scholar
  • 33 Hassiotou F, Hepworth AR, Metzger P. et al. Maternal and infant infections stimulate a rapid leukocyte response in breastmilk. Clin Transl Immunology 2013; 2 (04) e3
    CrossrefPubMedGoogle Scholar
  • 34 Leader S, Kohlhase K. Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000. J Pediatr 2003; 143 (05) S127-S132
    CrossrefPubMedGoogle Scholar
  • 35 Glezen WP, Paredes A, Allison JE, Taber LH, Frank AL. Risk of respiratory syncytial virus infection for infants from low-income families in relationship to age, sex, ethnic group, and maternal antibody level. J Pediatr 1981; 98 (05) 708-715
    CrossrefPubMedGoogle Scholar
  • 36 Jansson L, Nilsson P, Olsson M. Socioeconomic environmental factors and hospitalization for acute bronchiolitis during infancy. Acta Paediatr 2002; 91 (03) 335-338
    CrossrefPubMedGoogle Scholar