Rofo 2020; 192(S 01): S26
DOI: 10.1055/s-0040-1703182
Vortrag (Wissenschaft)
Herzdiagnostik/Gefäßdiagnostik
© Georg Thieme Verlag KG Stuttgart · New York

Non-contrast enhanced diagnosis of acute myocarditis based on the 17-segment heart model using 2D-feature tracking magnetic resonance imaging

M Salehi Ravesh
1  Klinik für Radiologie und Neuroradiologie, Universitätsklinikum Schleswig-Holstein (UKSH), Christian-Albrechts-Universität zu Kiel, Sektion biomedizinische Bildgebung, Molecular North Competence Center (MOIN CC), Kiel
,
M Eden
2  Universitätsklinikum Schleswig-Holstein, Klinik für Innere Medizin III mit den Schwerpunkten Kardiologie, Angiologie und internistische Intensivmedizin , Kiel
,
P Langguth
3  Universitätsklinikum Schleswig-Holstein, Klinik für Radiologie und Neuroradiologie, Kiel
,
T Piesch
3  Universitätsklinikum Schleswig-Holstein, Klinik für Radiologie und Neuroradiologie, Kiel
,
J Lehmann
4  Universitätsklinikum Schleswig-Holstein, Klinik für Radiologie und Nuroradiologie, Kiel
,
A Lebenatus
3  Universitätsklinikum Schleswig-Holstein, Klinik für Radiologie und Neuroradiologie, Kiel
,
J Grässner
3  Universitätsklinikum Schleswig-Holstein, Klinik für Radiologie und Neuroradiologie, Kiel
,
N Frey
2  Universitätsklinikum Schleswig-Holstein, Klinik für Innere Medizin III mit den Schwerpunkten Kardiologie, Angiologie und internistische Intensivmedizin , Kiel
,
O Jansen
3  Universitätsklinikum Schleswig-Holstein, Klinik für Radiologie und Neuroradiologie, Kiel
,
M Both
3  Universitätsklinikum Schleswig-Holstein, Klinik für Radiologie und Neuroradiologie, Kiel
› Author Affiliations
Further Information

Publication History

Publication Date:
21 April 2020 (online)

 
 

    Zielsetzung The aim of this study was to investigate the diagnostic value of myocardial deformation analysis based on the 17-segment heart model using non-contrast enhanced (CE) 2D tissue feature tracking (2D-FT) technique.

    Material und Methoden Seventy patients with suspected myocarditis underwent a cardiovascular magnetic resonance (CMR) examination at 1.5 Tesla. A contrast-agent-free part of this CMR protocol was additionally performed in forty healthy volunteers (HV). Besides standard CMR data sets, 2D-FT derived segmental and global longitudinal, radial, and circumferential deformation parameters were analyzed. The 2D-FT results were compared to the combined findings from CMR imaging and endomyocardial biopsy (EMB).

    Ergebnisse Patients were assigned to three groups depending on their ejection fraction (EF) (<40%, 40-55%, ≥55%). Compared to HV, impaired EF (<55%) was significantly correlated to reduced segmental and global strain and strain rate values. The circumferential deformation analysis was more sensitive to myocardial changes than longitudinal and radial analysis. The segmental strain/strain rate had an accuracy of 84.3%/70.0% for the diagnosis of an acute myocarditis, stated by EMB and CMR in 42 of 70 patients. In patients with preserved EF, acute myocarditis could be ruled out using only segmental strain analysis with a negative predictive value of 87.5%.

    Schlußfolgerungen In patients with suspected myocarditis, the deformation analysis based on the 17-segment heart model provides valuable information about functional myocardial inhomogeneity. This quantitative approach could be used in addition to the clinical standard CMR protocol and represents a promising tool in the framework of a prospective automatized multiparametric CMR imaging analysis.


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