Erratum: Treatment of Cancer-Associated Thrombosis: Beyond HOKUSAI

It has been brought to the publisher's attention, that there was an error in Table 1 of the above article, published in TH Open, Volume 3, Number 3, 2019, pages e309–e315 (DOI: 10.1055/s-0039-1696659). In the SELECT-D study, it should state “N = 406” instead of “N = 203”.

The correct table appears below.

Table 1 Protocol design of randomized control trials on anticoagulants for the treatment of cancer-associated thrombosis

Study (year)	Study drug/comparator	Patients	Methods/statistics	Primary endpoint	Secondary endpoints	Duration (mo)
ONCENOX39 N = 122 (2006)	Enoxaparin/warfarin	Active cancer, acute symptomatic VTE	Pilot feasibility	VTE recurrence	Major and minor bleeding	6
CANTHANOX25 N = 146 (2002)	Enoxaparin/warfarin	Active or treated cancer, PE, and/or DVT	S	Composite of major bleeding or recurrent VTE	Recurrent VTE Major bleeding	3
CLOT26 N = 672 (2003)	Dalteparin/warfarin	Active cancers, acute proximal symptomatic DVT or PE	Phase III/S	Symptomatic recurrence of DVT, PE, or both	Major bleeding Any bleeding	6
LITE CANCER27 N = 200 (2006)	Tinzaparin/warfarin	Cancer, acute proximal DVT	Phase III/S	Recurrent VTE or death	Major and minor bleeding	3
CATCH22 N = 900 (2015)	Tinzaparin/warfarin	Active cancers, acute proximal symptomatic DVT or PE	Phase III/S	VTE recurrence: proximal DVT, PE either symptomatic or incidental	Major bleeding CRNMB	6
SELECT-D23 N = 406 (2018)	Rivaroxaban/dalteparin	All active cancers, proximal DVT, PE, incidental PE	Pilot	VTE recurrence: proximal DVT, PE either symptomatic or incidental, and other sites	Major bleeding CRNMB	6
HOKUSAI-VTE Cancer21 N = 1,046 (2018)	Edoxaban/dalteparin	Active or history of cancer, acute symptomatic or incidental VTE	Phase III/NI	Composite of VTE recurrence (symptomatic or incidental) or major bleeding	VTE recurrence Major bleeding CRNMB	12
CARAVAGGIO35 N = 1,168 (2019)	Apixaban/dalteparin	Active or history of cancer, symptomatic or incidental proximal DVT or PE	Phase III/NI	Symptomatic or incidental VTE recurrence	Major bleeding	6

Abbreviations: CRNMB, clinically relevant nonmajor bleeding; DVT, deep-vein thrombosis; NI, noninferiority trial; PE, pulmonary embolism; S, superiority trial; VTE, venous thromboembolism.

 

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No conflict of interest has been declared by the author(s).