Homœopathic Links 2019; 32(03): 152-158
DOI: 10.1055/s-0039-1700537
Original Article
Thieme Medical and Scientific Publishers Private Ltd.

Usefulness of Robinia pseudoacacia in the Treatment of Gastroesophageal Reflux Disease

Radhika Agarwal
1   Central Council for Research in Homoeopathy (CCRH), 61-65, Sewa Marg, Opp ‘D’ Block, Institutional Area, Janakpuri, New Delhi 110058, India
› Author Affiliations
Further Information

Publication History

Publication Date:
12 December 2019 (online)

Abstract

Background and Objective Gastroesophageal reflux disease (GERD) is a common condition observed in daily clinical practice. This study was undertaken to explore the usefulness of Robinia pseudoacacia in the treatment of GERD. Traditionally, since many centuries, Robinia pseudoacacia has been in use for various gastric disturbances in physiological doses. This study is an effort to understand its utility in GERD when prescribed on homoeopathic indications.

Methods A prospective, observational study was conducted at Bakson Homeopathic College and Hospital, Greater Noida, Uttar Pradesh from 2016 to 2018. Patients who were 20 to 60 years of age suffering from heartburn and regurgitation were screened. Purposive sampling technique was used to enrol 30 patients (17 males and 13 females), who fulfilled the inclusion and exclusion criteria were enrolled in the study. The diagnosis was made on the basis of GERD questionnaire (GerdQ). Robinia pseudoacacia was prescribed in 6C potency in repeated doses to the enrolled patients on the clinical basis of symptom totality. The improvement in patients was assessed using GerdQ which was evaluated at baseline and after the 6 months treatment by using the paired ‘t’ test.

Results All enrolled cases completed the follow-up of 6 months. Out of the 30 cases, 1 case was cured, 26 showed a good improvement and 3 did not respond to the treatment. Overall, statistically significant difference was found in pre- and post-treatment GERDQ scores (p < 0.001).

Limitations include lack of control arm and prescription on common symptoms due to lack of characteristic symptoms.

Conclusion This study has shown positive results in terms of usefulness of Robinia pseudoacacia in the treatment of GERD. Further randomised controlled trial with long-term follow-ups need to be conducted for definite conclusions.

Financial Support and Sponsorship

No.


 
  • References

  • 1 Kahrilas PJ, Shaheen NJ, Vaezi MF. , et al; American Gastroenterological Association. American Gastroenterological Association Medical Position Statement on the management of gastroesophageal reflux disease. Gastroenterology 2008; 135 (04) 1383-1391 , 1391.e1–1391.e5
  • 2 Haslett C, Chilvers Edwin R, Nicholas AB, Colledge NR, Hunter JAA. Davidson's Principles and Practice of Medicine. 20th edition. London: Elsevier Ltd, Churchill Livingstone; 2006
  • 3 Burt WH. Characteristic Materia Medica, Reprint ed. New Delhi: B. Jain Publisher Pvt Ltd; 1993
  • 4 Blackwood A. The Food Tracts- it’s Ailments and Diseases of Peritoneum, Reprint ed. New Delhi: B. Jain Publisher Pvt Ltd; 1999
  • 5 Choudhuri NM. A Study on Materia Medica, Reprint ed. New Delhi: B. Jain Publisher Pvt Ltd; 2002
  • 6 Jones S. The Medical Genius - A Guide to the Cure. Ulan Press; 2012
  • 7 Zavala-Gonzales MA, Azamar-Jacome AA, Meixueiro-Daza A. , et al. Validation and diagnostic usefulness of gastroesophageal reflux disease questionnaire in a primary care level in Mexico. J Neurogastroenterol Motil 2014; 20 (04) 475-482
  • 8 Jones R, Junghard O, Dent J. , et al. Development of the GerdQ, a tool for the diagnosis and management of gastro-oesophageal reflux disease in primary care. Aliment Pharmacol Ther 2009; 30 (10) 1030-1038
  • 9 Wang HY, Leena KB, Plymoth A. , et al. Prevalence of gastroesophageal reflux disease and its risk factors in a community-based population in southern India. BMC Gastroenterol 2016; 16: 36
  • 10 Alrashed AA, Aljammaz KI, Pathan A. , et al. Prevalence and risk factors of gastroesophageal reflux disease among Shaqra University students, Saudi Arabia. J Family Med Prim Care 2019; 8 (02) 462-467
  • 11 Kristo I, Paireder M, Jomrich G. , et al. Modern esophageal function testing and gastroesophageal reflux disease in morbidly obese patients. Obes Surg 2019 . Doi: 10.1007/s11695-019-04020-1
  • 12 Sharara AI, Rustom LBO, Bou Daher H. , et al. Prevalence of gastroesophageal reflux and risk factors for erosive esophagitis in obese patients considered for bariatric surgery. Dig Liver Dis 2019; 51 (10) 1375-1379