Abstract
Central nervous system (CNS) BCGitis is a rare but a very severe complication of the
Bacille Calmette–Guerin (BCG) vaccine. It could be a diagnostic challenge that may
lead to a delay in treatment. A 5-month-old boy presented with infantile spasms, had
posted natal BCG vaccination and developed brain tuberculomas as brain BCGitis. Laboratory
findings were normal. He received 14 months of antitubercular regimen with good tolerance
and both clinical and radiological improvement. The main difficulty in brain BCGitis
is to make a diagnosis that requires histological or bacteriological examination.
A good evolution without sequel could be seen if it is treated early.
Keywords
epileptic spasms - BCGitis - brain tuberculomas - child