Endoscopy 2019; 51(04): S160-S161
DOI: 10.1055/s-0039-1681644
ESGE Days 2019 ePoster podium presentations
Friday, April 5, 2019 16:30 – 17:00: Colon capsule ePoster Podium 2
Georg Thieme Verlag KG Stuttgart · New York

DIABETES MELLITUS AND VIDEO CAPSULE ENDOSCOPY: SOME OF THEM JUST NEED MORE TIME

I Sergeev
1   Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba, Israel
,
A Stein
1   Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba, Israel
2   Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
,
Y Ringel
1   Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba, Israel
3   Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, United States
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Publikationsverlauf

Publikationsdatum:
18. März 2019 (online)

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    Aims:

    The aim of the study was to evaluate the influence of DM on gastric and small bowel transit times, and on VCE examination completion rate.

    Methods:

    In single center, retrospective study we investigated the records of patients who underwent VCE (PillCam, Given Imaging) for evaluation of iron deficiency between 2010 – 2017. Patients with history of gastric/colonic/small bowel surgery, Parkinson's disease, Crohn's disease, and active non-prostate malignancy were excluded. Demographic and VCE examination related data were collected. DM-variables of interest included disease duration, insulin use, presence of end-organ damage, peak and current HgA1c.

    Results:

    254 patients met the inclusion criteria. Forty seven percent had type 2 DM.

    Patients with diabetic neuropathy had prolonged small bowel transition time (SBTT) compared to non-DM patients (5.24+/-1.18 VS 4.38+/-1.34 hours, p = 0.02) and to DM patients without end-organ damage (5.24+/-1.18 VS 4.08+/-1.48 hours, p = 0.005). Likewise, SBTT was prolonged in insulin treated patients compared to non-DM patients (5.32+/-1.19 VS 4.38+/-1.34, p = 0.004) and to DM patients without insulin treatment (5.32+/-1.19 VS 4.23+/-1.59, p = 0.004).

    Retinopathy or nephropathy alone did not significantly influence SBTT. Gastric transit time was similar between DM and non-DM cohorts (0.54 +/-0.67 hours VS 0.6 +/-0.82 hours, p = 0.55), with no influence for DM characteristics.

    VCE completion was lower in patients with diabetic neuropathy compared to those without end-organ damage (87.5% VS 98%, p = 0.03). A trend for lower completion rate was noted in insulin treated patients and those with multiple end-organ damage.

    Conclusions:

    SBTT is significantly prolonged in DM patients with neuropathy or insulin treatment, leading to lower VCE completion rate in those patients. An a priori longer VCE recording time should be considered for patients with these conditions. For DM patients without end-organ damage or insulin treatment, transition times and VCE completion rates are similar to those without DM, and examination time adjustments are probably not needed.