Summary
347 patients with angina pectoris and 222 patients who had survived an attack of myocardial
infarction for at least 8 weeks have been under long-term treatment with dicumarol
or phenylindanedione. The annual mortality-rate was reduced to 5% in both groups.
Patients with angina pectoris show improvement in 47.7% of the cases, if the disease
is not older than 1 year before the start of treatment. Improvement was found in only
25% of the cases when the disease was older than 4 years. It was clearly evidenced
that anticoagulant treatment of angina pectoris is only useful when the disease is
not older than 2 to 3 years before starting treatment.