A Study of Three Cases of Familial Congenital Hypoprothrombinaemia (Factor II Deficiency)

Summary

Three cases of true congenital hypoprothrombinaemia are presented.

Studies were made to prove the deficiency of prothrombin in the patient’s plasma and to rule out deficiency of other clotting factors or the presence of abnormal anti-thrombin substances.

All the patients were of group B.

The results obtained confirm that the patients have a real prothrombin deficiency as the cause of a severe haemorrhagic disease.

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