Evaluation of Activity of Phospholipids in Blood Coagulation in Vitro

M. J Silver; D. L Turner; I Rodalewicz; N Giordano; R Holburn; S. F Herb; Francis E Luddy

doi:10.1055/s-0038-1654772

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1963; 10(01): 164-189
DOI: 10.1055/s-0038-1654772

Originalarbeiten — Original Article — Travaux Originaux

Schattauer GmbH

Evaluation of Activity of Phospholipids in Blood Coagulation in Vitro^[*]

M. J Silver

¹Cardeza Foundation and Department of Pharmacology. Jefferson Medical College, Philadelphia, Pa. and the Eastern Utilization Research and Development Division, U.S.D.A., Wyndmoor, Pa

,

D. L Turner

¹Cardeza Foundation and Department of Pharmacology. Jefferson Medical College, Philadelphia, Pa. and the Eastern Utilization Research and Development Division, U.S.D.A., Wyndmoor, Pa

,

I Rodalewicz

¹Cardeza Foundation and Department of Pharmacology. Jefferson Medical College, Philadelphia, Pa. and the Eastern Utilization Research and Development Division, U.S.D.A., Wyndmoor, Pa

,

N Giordano

¹Cardeza Foundation and Department of Pharmacology. Jefferson Medical College, Philadelphia, Pa. and the Eastern Utilization Research and Development Division, U.S.D.A., Wyndmoor, Pa

,

R Holburn

¹Cardeza Foundation and Department of Pharmacology. Jefferson Medical College, Philadelphia, Pa. and the Eastern Utilization Research and Development Division, U.S.D.A., Wyndmoor, Pa

,

S. F Herb

¹Cardeza Foundation and Department of Pharmacology. Jefferson Medical College, Philadelphia, Pa. and the Eastern Utilization Research and Development Division, U.S.D.A., Wyndmoor, Pa

,

Francis E Luddy

¹Cardeza Foundation and Department of Pharmacology. Jefferson Medical College, Philadelphia, Pa. and the Eastern Utilization Research and Development Division, U.S.D.A., Wyndmoor, Pa

› Author Affiliations

Abstract

Summary

1. The effects of phospholipids, solubilized by different methods in different clotting tests are presented.

2. Complete fatty acid analysis of a phosphatidylserine fraction from beef brain is given.

3. Data relating electric charge of phospholipid particles to activity in clotting are presented.

4. A critical discussion of the factors which influence the activity of phospholipids in blood clotting terminates the paper.

Full Text

References

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Evaluation of Activity of Phospholipids in Blood Coagulation in Vitro[*]

Evaluation of Activity of Phospholipids in Blood Coagulation in Vitro^[*]