Fibrinolytic Activator, Glutamic Oxaloacetic Transaminase and Potassium in Myocardial Tissue at Various Stages of Human Myocardial Infarction

Summary

1. The concentrations of GO transaminase, potassium and plasminogen activator have been estimated in tissue homogenates from different zones of 7 human myocardial infarcts of varying age.

2. Significantly decreased values for GO transaminase, plasminogen activator and potassium were found in areas with fully developed necrosis.

3. Ischemic areas showed a less marked but significant decrease in GO transaminase and potassium concentrations, whereas the plasminogen activator was normal or slightly increased.

4. Fibrosed infarcts showed increased concentrations of plasminogen activator.

 

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