Activation of Hageman Factor by α-Adrenergic Stimulation

D. G McKay; J.-G Latour; Mary H. Parrish

doi:10.1055/s-0038-1654067

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1970; 23(03): 417-422
DOI: 10.1055/s-0038-1654067

Originalarbeiten – Original Articles – Travaux Originaux

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Activation of Hageman Factor by α-Adrenergic Stimulation

D. G McKay M. D.,

¹Department of Pathology University of California School of Medicine San Francisco General Hospital 1001 Potrero Avenue San Francisco, California 94110

,

J.-G Latour Ph. D.

¹Department of Pathology University of California School of Medicine San Francisco General Hospital 1001 Potrero Avenue San Francisco, California 94110

,

Mary H. Parrish B. S.

¹Department of Pathology University of California School of Medicine San Francisco General Hospital 1001 Potrero Avenue San Francisco, California 94110

› Author Affiliations

Abstract

Summary

The infusion of epinephrine in high doses produces disseminated intravascular coagulation by activation of Hageman factor. The effect is blocked by phenoxybenz-amine and is therefore due to stimulation of α-adrenergic receptor sites.

Full Text

References

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