Thromb Haemost 1968; 19(03/04): 423-429
DOI: 10.1055/s-0038-1651220
Originalarbeiten – Original Articles – Travaux Originaux
Schattauer GmbH

Preparation and Standardization of a Stable AHF Plasma

G. M Thelin1
1   Department of Coagulation, Research Division, Hyland Division Travenol Laboratories, Inc., Los Angeles, California
,
Los Angeles, California› Author Affiliations

Presented in part at the XIth Congress of the International Society of Blood Transfusion, Sydney, Australia, August 1966.
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Publication History

Publication Date:
27 June 2018 (online)

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Summary

A stable, lyophilized AHF reference plasma has been prepared from pooled plasma from at least 50 normal healthy donors and standardized against a primary standard of fresh plasma from 20 healthy male donors aged 20 to 40. Average AHF potency of a typical lot is 98.8%, and moisture content is less than 0.5%. Under storage at -25° C, this AHF reference plasma is stable for at least 18 months. It has been used in several major coagulation laboratories, and has given consistently satisfactory and reproducible results in AHF assays.

1 Deceased.


Address reprint requests to Edward Shanbrom, M. D., Research Division, Hyland Division Travenol Laboratories, Inc., 4501 Colorado Boulevard, Los Angeles, California, 90039, USA.