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Thromb Haemost 1968; 19(01/02): 001-011
DOI: 10.1055/s-0038-1650203
Originalarbeiten – Original Articles – Travaux Originaux
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Localization of Inhibition of Platelet Aggregation by Incubation of Platelet Rich EDTA-Plasma at 37°C

R Gross
1   Medical Clinic of the University of Cologne (Head: Prof. Dr. R. Gross)
,
G Niemeyer
1   Medical Clinic of the University of Cologne (Head: Prof. Dr. R. Gross)
,
H Reuter
1   Medical Clinic of the University of Cologne (Head: Prof. Dr. R. Gross)
› Author Affiliations
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Publication History

Publication Date:
27 June 2018 (online)

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Summary

By photometric and microscopic technics investigations have been carried out to determine the nature of the inhibition of platelet aggregation caused by incubating platelet rich EDTA-plasma at 37° C. The results clearly indicate that the inhibition must arise from alterations in the platelets themselves. The appearance of an inhibitory substance in plasma and the release of such a substance from the platelets into the plasma have been excluded. Addition of ADP to the inhibited platelets did not influence the inhibition of platelet aggregation.

 

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