Thromb Haemost 1972; 27(03): 490-501
DOI: 10.1055/s-0038-1649388
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

The Adsorption of Blood Coagulation Factors II, VII, IX and X from Human Plasma to Aluminium Hydroxide

A. C. W Swart
1   Laboratory of Blood Coagulation Biochemistry, Dept. of Internal Medicine, University Hospital, Leiden, The Netherlands
,
B. H. M Klaassen
1   Laboratory of Blood Coagulation Biochemistry, Dept. of Internal Medicine, University Hospital, Leiden, The Netherlands
,
C. H. F Bloys-van Treslong-De Groot
1   Laboratory of Blood Coagulation Biochemistry, Dept. of Internal Medicine, University Hospital, Leiden, The Netherlands
,
H. C Hemker
1   Laboratory of Blood Coagulation Biochemistry, Dept. of Internal Medicine, University Hospital, Leiden, The Netherlands
› Author Affiliations
Further Information

Publication History

Publication Date:
29 June 2018 (online)

Summary

The influence of pH, adsorption time, ionic strength, buffer type and plasma concentration on adsorption and elution of the factors of the prothrombin complex from normal human ACD plasma onto A1(OH)3 is investigated. Reproducible small differences are found between the behaviour of the four factors II, VII, IX, and X.