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Thromb Haemost 1972; 27(02): 278-291
DOI: 10.1055/s-0038-1649367
DOI: 10.1055/s-0038-1649367
Originalarbeiten – Original Articles – Travaux Originaux
The Effect of Alpha- and Beta-Receptor Blocking Agents on Collagen-Induced Platelet Release Reaction (A Comparison with ADP-Induced Release)
Further Information
Publication History
Publication Date:
29 June 2018 (online)
Summary
The mechanism of the platelet release reaction, induced by collagen, is in certain respects different from that of ADP. Besides other facts, the PF 4 release and the availability of PF 3 and APh are not influenced by the concentrations of alpha or beta-receptor blocking agents which clearly interfere with the ADP-induced release.
The possible role of thrombosthenin (or its alpha-receptors in the participation of the release reaction is discussed.
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