Thromb Haemost 1973; 30(01): 173-177
DOI: 10.1055/s-0038-1649114
Original Article
Schattauer GmbH

The Migration of Human Platelets in Vitro

Paul Nathan
1   Shriners Burns Institute, Cincinnati Unit, and Departments of Physiology and Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.
› Author Affiliations
Further Information

Publication History

Received for publication 23 February 1973

Accepted for publication 22 March 1973

Publication Date:
30 June 2018 (online)

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Summary

A simple procedure is described for measuring migration of human platelets in vitro. Migration increased with temperature reaching maximum values at approximately 30 °C. Addition of normal plasma to the incubation chambers increased migration in all tests and the increase reached twice the control values in 3 of 4 tests. The rate of migration in vitro was relatively rapid for the first 12 hrs. of incubation and then continued at a slower rate for at least an additional 12 hours.