Thromb Haemost 1973; 30(01): 173-177
DOI: 10.1055/s-0038-1649114
Original Article
Schattauer GmbH

The Migration of Human Platelets in Vitro

Authors

  • Paul Nathan

    1   Shriners Burns Institute, Cincinnati Unit, and Departments of Physiology and Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.
Further Information

Publication History

Received for publication 23 February 1973

Accepted for publication 22 March 1973

Publication Date:
30 June 2018 (online)

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Summary

A simple procedure is described for measuring migration of human platelets in vitro. Migration increased with temperature reaching maximum values at approximately 30 °C. Addition of normal plasma to the incubation chambers increased migration in all tests and the increase reached twice the control values in 3 of 4 tests. The rate of migration in vitro was relatively rapid for the first 12 hrs. of incubation and then continued at a slower rate for at least an additional 12 hours.