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Thromb Haemost 1973; 29(02): 445-449
DOI: 10.1055/s-0038-1647784
DOI: 10.1055/s-0038-1647784
Original Article
Enhancement by ADP of Thrombin-induced Aggregation in ADP-refractory Platelets
Further Information
Publication History
Received for publication
09 October 1972
Publication Date:
24 July 2018 (online)
Summary
In ADP-refractory rat platelets, thrombin-induced aggregation is enhanced in the presence of ADP and inhibited in the absence of ADP. Two mechanisms are proposed for thrombin-induced platelet aggregation: one through ADP release which may become refractory, and a second mechanism in which thrombin acts synergistieally with ADP.
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