Keywords
Karnofsky performance scoring - medulloblastomas - midline posterior fossa tumor
Introduction: Posterior fossa tumors constitute 50% of childhood brain. Medulloblastomas are the
most common midline posterior fossa tumor in childhood. This study is designed to
determine the frequency and types of midline posterior cranial fossa tumors and study
the different clinical presentation of these tumors, surgical complications, and final
outcome as measured by the Karnofsky performance scoring.
Methodology/Description: After permission from ethics committee, the study was performed as a prospective
observational study on 60 patients admitted from March 2015 to March 2017 and operated
for midline posterior fossa tumors, at the KIMS Hospital, Secunderabad. The data were
entered on the predesigned form. Descriptive statistics were used for demographics.
Data were analyzed using the EXCEL and SPSS softwares.
Results: The gender distribution was 38 male and 22 female patients with equal adults and
children. Maximum belonged to the age group of 0 to 12 years. Of these, 52 patients
presented with headache and 40 had vomiting. Blurring of vision was seen in 22 patients.
Most common midline posterior fossa tumor was medulloblastoma. Postoperative hydrocephalus
and seizures were seen in six patients. Out of 60 patients, 12 patients had poor outcome
versus 48 patients with good outcome on the Karnofsky performance status.
Conclusion: Midline posterior fossa tumors were more common in males. Symptoms of raised ICP
and cerebellar symptoms were most common presentations. Headache and histopathology
of tumor: high grade or low grade shows statistically significant correlation with
outcome of patients as measured with the Karnofsky performance scoring. As our study
was of small duration, long-term study can give better results
