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Vet Comp Orthop Traumatol 1996; 09(03): 134-9
DOI: 10.1055/s-0038-1632518
Original Research
Schattauer GmbH

The Ovine Stifle as a Model for Human Cruciate Ligament Surgery

W.J.P. Radford
1   From the 1Biomechanics Section, Department of Mechanical Engineering, Imperial College of Science, Technology and Medicine, London, England
,
A. A. Amis
1   From the 1Biomechanics Section, Department of Mechanical Engineering, Imperial College of Science, Technology and Medicine, London, England
,
A. C. Stead
2   Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, Edinburgh, Scotland
› Author Affiliations
Further Information

Publication History

Received for publication 20 September 1995

Publication Date:
23 February 2018 (online)

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Summary

This study evaluated the anatomy and biomechanics of the ovine stifle, with a view to its use as a model of the human knee joint.

Stifles were dissected to define the internal anatomy, concentrating on the cruciate ligaments. The cranial cruciate ligament (CraCL) was assessed biomechanically at 30° and 90° flexion, intact, with the craniomedial bundle (CraMB) divided, and after complete transection. Craniocaudal (C-C) and internal-external rotatory stability were assessed. The tensile strength of the CraCL was determined.

The morphology of the ovine stifle was similar to the human knee. Sequential sectioning of the bundles of the CraCL caused increasing cranial laxity of the joint. Rotational laxity also increased as the CraCL was divided, as well as with progressive joint flexion. It was concluded that the ovine stifle is a valid animal model for the human knee for work on the cruciate ligaments.

The anatomy and biomechanics of the ovine stifle were studied, with a view to assessing the suitability of the joint as a surgical model for the cruciate ligaments of the human knee. The ligaments, joint stability and cranial cruciate ligament strength were measured. It was concluded that the ovine stifle is a valid model of the human knee for this purpose.

Keywords

Cruciate ligament - ovine - stifle joint - anatomy - biomechanics
 

  • REFERENCES

  • 1 Amis AA. Anterior cruciate ligament replacement. Knee stability and the effects of implants. J Bone Joint Surg [B] 1989; 71 B 819-24.
    PubMedGoogle Scholar
  • 2 Amis AA, Dawkins GPC. Functional anatomy of the anterior cruciate ligament: fibre bundle actions related to ligament replacements and injuries. J Bone Joint Surg [Br] 1991; 73: 260-7.
    PubMedGoogle Scholar
  • 3 Amis AA, Camburn M, Kempson SA, Radford WJP, Stead AC. Anterior cruciate ligament replacement with polyester fibre - a long term study of tissue reactions and joint stability in sheep. J Bone Joint Surg [Br] 1992; 74: 605-13.
    PubMedGoogle Scholar
  • 4 Arnoczky SP, Marshall JL. The cruciate ligaments of the canine stifle: An anatomical and functional analysis. Am J Vet Res 1977; 38: 1807-14.
    PubMedGoogle Scholar
  • 5 Bercovy M, Goutallier D, Voisin MC, Geiger D, Blanquaert D, Gaudichet A, Patte D. Carbon-PGLA prostheses for ligament reconstruction. Experimental basis and short-term results in man. Clin Orthop 1985; 196: 159-68.
    PubMedGoogle Scholar
  • 6 Bosch U, Decker B, Kasperczyk W, Oestern HJ, Tscherne H. Biological aspects of longterm failure of autografts after cruciate ligament replacement. Arch Orthop Trauma Surg 1989; 108: 368-72.
    CrossrefPubMedGoogle Scholar
  • 7 Brantigan OC, Voshell AF. The mechanics of the ligaments and menisci of the knee joint. J Bone Joint Surg 1941; 23: 44-66.
    PubMedGoogle Scholar
  • 8 Butler DL, Noyes FR, Grood ES. Ligamentous restraints to anterior-posterior drawer in the human knee. A biomechanical study. J Bone Joint Surg [Am] 1980; 62: 259-70.
    CrossrefPubMedGoogle Scholar
  • 9 Claes L, Durselen L, Kiefer H, Mohr W. The combined anterior cruciate and medial collateral ligament replacement by various materials: A comparative animal study. J Biomed Mater Res 1987; 21: 319-43.
    PubMedGoogle Scholar
  • 10 Claes L, Neugebauer R. In vivo and in vitro investigation of the long-term behaviour and fatigue strength of carbon fiber ligament replacement. Clin Orthop 1985; 196: 99-111.
    PubMedGoogle Scholar
  • 11 Cooke PH. Goodship AE. Biomechanical compatibility of cruciate ligament prostheses. Eng Med 1986; 15: 95-8.
    CrossrefPubMedGoogle Scholar
  • 12 Figgie HE, Bahnuik EH, Heiple KG, Davy DT. The effects of tibio-femoral angle on the failure mechanics of the canine anterior cruciate ligament. J Biomech 1986; 19: 89-91.
    CrossrefPubMedGoogle Scholar
  • 13 Getty R. The Anatomy of the Domestic Animals. Vol 1. Philadelphia, London, Toronto: Saunders; 1975: 787-90.
    Google Scholar
  • 14 Girgis FG, Marshall JL, AI Monajem RS. The cruciate ligaments of the knee joint. Anatomical, functional and experimental analysis. Clin Orthop 1975; 106: 216-31.
    CrossrefPubMedGoogle Scholar
  • 15 Heffron LE, Campbell JR. Morphology, histology and functional anatomy of the canine cranial cruciate ligament. Vet Rec 1978; 102: 280-3.
    CrossrefPubMedGoogle Scholar
  • 16 Hefzy MS, Grood ES, Noyes FR. Factors affecting the region of most isometric femoral attachments. Part II: the anterior cruciate ligament. Am J Sports Med 1989; 17: 208-16.
    CrossrefPubMedGoogle Scholar
  • 17 Hollis JM, Lyon RM, Marcin Horibe S, Lee EB, Woo SL-Y. Effects of age and loading axis on the failure properties of the human ACL. Trans Orthop Res Soc 1988; 13: 18
    PubMedGoogle Scholar
  • 18 Jenkins DHR. The induction of new anterior cruciate ligaments in the sheep and the clinical use of filamentous carbon fibre in the human. J Bone Joint Surg [Br] 1979; 61: 120
    PubMedGoogle Scholar
  • 19 Lam SJS. Reconstruction of the anterior cruciate ligament using the Jones procedure and its Guy’s Hospital modification. J Bone Joint Surg [Am] 1968; 58: 1213-24.
    PubMedGoogle Scholar
  • 20 May NDS. The Anatomy of the Sheep. 2nd ed. Brisbane: University of Queensland Press 1964; 102-22. 311-28
    PubMedGoogle Scholar
  • 21 Nickel R, Schummer A, Seiferle E, Frewein J, Wilkins H, Wille K-H. The Locomotor System of the Domestic Mammals. Translated by Siller WG, Stokoe WM. Berlin, Hamburg: Springer; 1986: 205-6.
    Google Scholar
  • 22 Noyes FR, DeLucas JL, Torvik PJ. Biomechanics of anterior cruciate ligament failure: An analysis of strain-rate sensitivity and mechanisms of failure in primates. J Bone Joint Surg [Am] 1974; 56: 236-53.
    CrossrefPubMedGoogle Scholar
  • 23 Noyes FR, Grood ES. The strength of the anterior cruciate ligament in humans and rhesus monkeys. Age-related and speciesrelated changes. J Bone Joint Surg [Am] 1976; 58: 1074-82.
    CrossrefPubMedGoogle Scholar
  • 24 Race A, Amis AA. The mechanical properties of the two bundles of the human posterior cruciate ligament. J. Biomechs 1994; 27: 13-24.
    PubMedGoogle Scholar
  • 25 Radford WJP, Amis AA. Biomechanics of a double prosthetic ligament in the anterior cruciate deficient knee. J Bone Joint Surg [Br] 1990; 73: 1038-43.
    PubMedGoogle Scholar
  • 26 Radford WJP, Amis AA, Kempson SA, Stead AC, Camburn M. A comparative study of single and double-bundle ACL reconstruction in sheep. Knee Surg, Sports Traumatol, Arthroscopy 1994; 2: 94-9.
    CrossrefPubMedGoogle Scholar
  • 27 Rogers GJ, Milthorpe BK, Muratore A, Schindhelm K. Measurement of mechanical properties of the anterior cruciate ligament. Austral Phys Eng Sci Med 1985; 8: 168-72.
    PubMedGoogle Scholar
  • 28 Trent PS, Walker PS, Wolf B. Ligament length patterns, strength, and rotational axes of the knee joint. Clin Orthop 1976; 117: 263-70.
    PubMedGoogle Scholar
  • 29 Welsh RP. Knee joint structure and function. Clin Orthop 1980; 147: 7-14.
    PubMedGoogle Scholar