Panhypopituitarism as a Consequence of Metastase of Breast Cancer in Sella turcica

Summary

A 49-year-old female with breast cancer after mastectomy and chemotherapy was found suffering from diabetes insipidus and panhypopituitarism syndrome. Whole body bone scan showed hyperfixation in sella turcica. This site is extremely rare, especially in breast cancer metastases.

Zusammenfassung

Eine 49jährige Frau mit Brustkrebs litt nach Mastektomie und Chemotherapie an Diabetes insipidus und Hypophysenunterfunktions-Syn-drom. Das Ganzkörperskelettszintigramm zeigte eine Hyperfixation in der Sella turcica. Diese Stelle ist äußerst selten, insbesondere bei Brustkrebsmetastasen.

Key words

Panhypopituitarism - breast cancer - skeletal metastases - sella turcica

Schlüsselwörter

Hypophysenunterfunktions-Syndrom - Brustkrebs - Knochenmetastasen - Sella turcica

• References

• 1 Coleman M, Mattheiew W. Imaging techniques in breast cancer: Workshop report. Eur J Cancer Clin Oncol 1988; 24: 69-71.
• 2 Fogelman I, Coleman R. The bone scan and breast cancer. In: Nuclear medicine annual. Freeman LM, Weissman HS. (eds). New York: Raven Press; 1988: 1-38.
• 3 Coleman RE, Rusens RD, Fogelman I. Reappraisal of the baseline bone scan in breast cancer. J Nucl Med 1988; 29: 1045-9.
• 4 Harinder SB, Sisley JF, Johnson RM. Value of preoperative bone and liver scans and alkaline phosphatase in the evaluation of breast cancer patients. Am J Surg 1993; 165: 221-3.
• 5 Cox MR, Gilliand R, Odling-Smee GW, Spence RAJ. An evaluation of radionuclide bone scanning and liver ultrasonography for staging breast cancer. Aust N Z J Surg 1992; 62: 550-5.
• 6 Predazinni A, Gelber R, Isley M, Castiglione M, Goldhirsch A. First repeated base scan in the observation of patients with operable breast cancer. J Clin Oncol 1986; 4: 389-94.
• 7 Pandya KJ, McFadden ET, Kalish LA, Tormey DC, Taylor SG 4th, Falkson G. A retrospective study of the earliest indicators of recurrence in patients on Eastern cooperative oncology group adjuvant chemotherapy trials for breast cancer. Cancer 1985; 55: 202-5.
• 8 Bledin AG, Kim MPE, Haynie TP. Base scintigraphic finding related to unilateral mastectomy. Eur J Nucl Med 1982; 7: 500-1.
• 9 Milbrath JR, Bragg DG, Youker JE. Breast Cancer. In: Oncologic Imaging. Bragg DG, Rubin P, Youker JE. (eds). Oxford: Pergamon Press Inc; 1984: 173-205.