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Nuklearmedizin 1987; 26(02): 58-67
DOI: 10.1055/s-0038-1628865
Review Articles
Schattauer GmbH

SPECT – physikalische und technische Voraussetzungen

P. Müller St.
1   Abteilung Nuklearmedizin, Universitätsklinikum Essen, BRD
,
H. Creutzig
1   Abteilung Nuklearmedizin, Universitätsklinikum Essen, BRD
› Author Affiliations
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Publication History

Publication Date:
04 February 2018 (online)

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  • LITERATUR

  • R1 Anger H. O. Radioisotope cameras. In Instrumentation in Nuclear Medicine. Hine H. G. ed 485-552 Academic Press; New York: 1964
    Google Scholar
  • R2 Axelsson B, Msaki P, Israelson A. Subtraction of Compton-scattered photons in single-photon emission computerized tomography. J. nucl. Med 1984; 25: 490-4.
    Google Scholar
  • R3 Barrett H. H, Swindel W. Radiological Imaging. Academic Press; New York: 1981
    Google Scholar
  • R4 Beck J. W, Jaszczak R. J, Coleman R. E, Starmer C. F, Nolte L. W. Analysis of SPECT including scatter and attenuation using sophisticated Monte Carlo modelling methods. IEEE Trans, nucl. Sei 1982; NS-29 506-11.
    Google Scholar
  • R5 Beck R. N, Zimmer L. T, Charleston D. B. Advances in fundamental aspects of medical imaging systems and techniques. In Medical Radioisotope Scintigraphy I. 3-45 IAEA, Vienna; 1973
    Google Scholar
  • R6 Bellini S, Piacentini M, Cafforio C, Rocca F. Compensation of tissue absorption in emission tomography. IEEE Trans. Acoust. Speech. Sig. Proc 1979; ASSP-27 213-8.
    Google Scholar
  • R7 Bracewell R. N. The Fourier Transform and Its Applications. McGraw Hill, New York; 1978
    Google Scholar
  • R8 Budinger T. F, Gullberg G. T. Transverse section reconstruction of gamma-ray emitting radionuclides in patients. In Reconstruction Tomography in Diagnostic Radiology and Nuclear Medicine. Ter-Pogossian M. M. ed 33-48 University Park Press, Baltimore; 1977
    Google Scholar
  • R9 Budinger T. F, Derenzo S. E, Greenberg W. L, Gullberg G. T, Huesman R. H. Quantitative potentials of dynamic emission computed tomography. J. nucl. Med 1978; 19: 309-15.
    Google Scholar
  • R10 Burgess A. E, Jennings R. G, Wagner R. F. A statistical efficiency. A measure of human visual signal detection performance. J. appl. Phot. Eng 1982; 8: 76-8.
    Google Scholar
  • R11 Burgess A. E. Effect of quantization noise on visual signal detection in noisy images. J. opt. Soc. Am 1985; A/2 1424-8.
    Google Scholar
  • R12 Chang L. T. A method for attenuation correction in radionuclide computed tomography. IEEE Trans, nucl. Sei 1978; NS-25 638-43.
    Google Scholar
  • R13 Chesler D. A, Riederer S. J, Pelc N. J. Noise due to photon counting statistics in computed X-ray tomography. J. Comp. Assist. Tom 1977; 1: 64-74.
    Google Scholar
  • R14 Coleman R. E, Greer K. L, Drayer B. P. et al.: Collimation for 123I SPECT imaging. In Emission Computed Tomography, Current Trends. Esser P. D. ed 135-45 Society of Nuclear Medicine; New York: 1983
    Google Scholar
  • R15 DeBruine J. F, Van Royen E. A, Vyth A, DeJong J. M.BV. Van der Schoot 201Thallium diethyldithiocarba- mate: An alternative to 123I N-isopropyl p-iodoamphetamine. J. nucl. Med 1985; 26: 925-30.
    Google Scholar
  • R16 Eckelman W. C, Reba R. C, Rzeszotarski W. J. et al.: External imaging of cerebral muscarinic acetylcholine receptors. Science 1984; 223: 291-3.
    CrossrefGoogle Scholar
  • R17 Egbert S. D, May R. S. An integral-transport method for Compton scatter correction in emission computed tomography. IEEE Trans, nucl. Sei 1980; NS-27 543-54.
    Google Scholar
  • R18 Ell P. J, Hocknell J. M.L, Jarritt P. H. et al.: A 99Tc labeled radiotracer for the investigation of cerebrovascular disease. J. nucl. Med. Comm 1985; 6: 437-41.
    Google Scholar
  • R19 Fahey F. H, Zimmerman R. E, Judy P. F, Lanza R. C. Energy resolution in a high pressure gas scintillation proportional chamber. Med. Phys 1986; 13: 25-34.
    CrossrefGoogle Scholar
  • R20 Floyd C. E, Jaszczak R. J, Harris C. C, Coleman R. E. Energy spatial d. i.stribution of multiple order Compton scatter in SPECT: A Monte Carlo investigation. Phys. Med. Biol 1984; 29: 1217-30.
    CrossrefGoogle Scholar
  • R21 Floyd C. E, Jaszczak R. J, Greer K. L, Coleman R. E. Deconvolution of Compton scatter in SPECT. J. nucl. Med 1985; 26: 403-8.
    Google Scholar
  • R22 Floyd C. E, Jaszczak R. J, Greer K. L, Coleman R. E. Inverse Monte Carlo as a unified reconstruction algorithm for ECT. J. nucl. Med 1986; 27: 1577-86.
    Google Scholar
  • R23 DeBruin J. F, Van Royen E. A, Vyth A. et al.: Thallium-201 diethyl-dithio carbamate. An alternative to 123l-N-isopropyl-p-iodo-amphetamine. J. Nucl. Med 1985; 26: 925-30.
    Google Scholar
  • R24 Geman S, McClure D. E. Bayesian image analysis: An application to single photon emission tomography. Proc. Amer. Stat. Assoc. Stat. Comp. 1985
    Google Scholar
  • R25 Gottschalk S. C, Salem D, Lim C. B, Wake R. H. SPECT resolution and uniformity improvements by noncircular Orbit. J. nucl. Med 1983; 24: 822-8.
    Google Scholar
  • R26 Green D. M, Swets J. A. Signal Detection Theory and Psychophysics. Wiley, New York: 1966
    Google Scholar
  • R27 Gullberg G. T, Budinger T. F. The use of filtering methods to compensate for constant attenuation in single-photon emission computed tomography. IEEE Trans. Biomed. Eng 1981; BME-28 142-57.
    Google Scholar
  • R28 Gullberg G. T, Malko J. A, Eisner R. L. sBoundary determination methods for attenuation correction in single photon emission computed omography. In Emission Computed Tomography, Current Trends. Esser P. D. ed 135-45 Society of Nuclear Medicine; New York: 1983
    Google Scholar
  • R29 Gullberg G. T, Crawford C. R, Tsui B. M.W. Reconstruction algorithm for fan beam with a displaced center-of- rotation. IEEE Trans. Med. Im 1986; MI-5 23-9.
    Google Scholar
  • R30 Hanson K. M. Detectability in computed tomographic images. Med. Phys 1979; 6: 441-51.
    CrossrefGoogle Scholar
  • R31 Hanson K. M. Variations in task and the ideal observer. Proc. of Society of Photo-optical Instrumentation Engineers (Application of optical instrumentation in medicine XI). SPIE Proc. 419 Medicine 1983; XI: 6067.
    Google Scholar
  • R32 Hanson K. M. Optimal object and edge localization in the presence of correlated noise. SPIE Proc 1984; 454: 9-17.
    Google Scholar
  • R33 Hawman E. G, Hsieh J. An astigmatic collimator for high sensitivity SPECT of the brain. J. nucl. Med 1986; 27: 930.
    Google Scholar
  • R34 Hoffman E. J, Huang S. C, Phelps M. E. Quantitation in positron emission tomography: I. Effect of object size. J. Comp. Assist. Tom 1979; 3: 299-308.
    Google Scholar
  • R35 Hsieh J, Hawman E. G. Convolution reconstruction for astigmatic collimator imaging. J. nucl. Med 1986; 27: 896.
    Google Scholar
  • R36 Huang S. C, Hoffman E. J, Phelps M. E, Kuhl D. E. Quantitation in positron emission computed tomography:II. Effects of inaccurate attenuation correction. J. Comp. Assist. Tom 1979; 3: 804-14.
    Google Scholar
  • R37 Huang S. C, Hoffman E. J, Phelps M. E, Kuhl D. E. Quantitation in positron emission computed tomography: III. Effect of sampling. J. Comp. Assist. Tom 1979; 3: 804-14.
    Google Scholar
  • R38 Huesman R. H. The effects of a finite number of projection angles and finite lateral sampling of projections on the propagation of statistical errors in transverse section reconstruction. Phys. Med. Biol 1977; 22: 511-21.
    CrossrefGoogle Scholar
  • R39 Jaszczak R. J, Chang L. T, Murphy P. H. Single-photon emission computed tomography using multi-slice fan beam collimators. IEEE Trans, nucl. Sei 1979; NS-26 610-8.
    Google Scholar
  • R40 Jaszczak R. J, Coleman R. E, Whitehead F. R. Physical factors affecting quantitative measurements using camera-based single-photon emission computed tomography (SPECT). IEEE Trans, nucl. Sei 1981; NS-28 69-80.
    Google Scholar
  • R41 Jaszczak R. J, Greer K. L, Floyd C. E, Harris C. C, Coleman C. E. Improved SPECT quantitation using compensation for scattered photons. J. nucl. Med 1984; 25: 893-900.
    Google Scholar
  • R42 Jaszczak R. J, Floyd C. E, Coleman R. E. Scatter compensation techniques for SPECT. IEEE Trans, nucl. Sei 1985; NS-32 786-93.
    Google Scholar
  • R43 Jaszczak R. J, Floyd C. E, Manglos S. H, Greer K. L, Coleman R. E. Cone beam collimation for single photon emission computed tomography: Analysis, simulation, and image reconstruction using filtered backprojection. Med. Phys 1986; 13: 484-9.
    CrossrefGoogle Scholar
  • R44 Jones A. G, Abrams M. J, Davison A. et al.: Biological studies of a new class of technetium complexes: the hexakis (alkylisonitrile) technetium (I) cations. Int. J. nucl. Med. Biol 1984; 11: 225-34.
    CrossrefGoogle Scholar
  • R45 Judy P. F, Swensson R. G, Szulc M. Lesion detection and signal-to- noise ratio in CT images. Med. Phys 1981; 8: 13-23.
    CrossrefGoogle Scholar
  • R46 Judy P. F, Swensson R. G. Detection of small focal lesions in CT images: Effects of reconstruction filters and visual display windows. Brit. J. Radiol 1985; 58: 137-45.
    CrossrefGoogle Scholar
  • R47 Kaufman L, Champ D. C, Quaid J. H. et al.: Delay line readouts for high purity germanium medical imaging cameras. IEEE Trans, nucl. Sei 1974; NS-21 652-7.
    Google Scholar
  • R48 Kessler M. K, Ellis J. R, Murray E, Analysis o. f. emission tomographic scan data. Limitations imposed by resolution and background. J. Comp. Assist. Tom 1984; 8: 514-22.
    Google Scholar
  • R49 Kijewski M. F, Judy P. F. The effects of misregistration of the projections on spatial resolution of CT scanners. Med. Phys 1983; 10: 169-75.
    CrossrefGoogle Scholar
  • R50 Kijewski M. F, Mueller S. P, Holman B. L. Effects of aliasing on the image noise-power spectrum for ECT. Radiology 1985; 62: 157(P).
    Google Scholar
  • R51 Kijewski M. F, Judy P. F. The noise-power spectrum of CT images. Med. Phys. (in press)
    Google Scholar
  • R52 King M. A, Schwinger R. B, Penney B. C, Doherty P. W, Bianco J. A. Digital restoration of 111Indium and 123Iodine SPECT images with optimized Metz filters. J. nucl. Med 1986; 27: 1327-36.
    Google Scholar
  • R53 Kuhl D. E, Sanders T. D, Edwards R. Q, Meckler P. T. Failure to improve observer performance with scan smoothing. J. nucl. Med 1972; 13: 752-7.
    Google Scholar
  • R54 Kung H. F, Tramposch K. M, Blau M. A new brain perfusion imaging agent: [123I] HIPDM; N,N,N’-trimethyl- N’-[2-hydroxy-3-methyl-5-iodobenzyl]- 1,3 propanediamine. J. nucl. Med 1983; 24: 66-72.
    Google Scholar
  • R55 Lange K, Carson R. EM reconstruction algorithms for emission and transmission tomography. J. Comp. Assist. Tom 1984; 8: 306-16.
    Google Scholar
  • R56 Larsson S. A. Gamma Camera Emission Tomography. Acta Radiol 1980; Suppl 363.
    Google Scholar
  • R57 Larsson S. A, Bergstrand G, Bergstedt H. et al.: A special cut-off gamma camera for high-resolution SPECT of the head. J. nucl. Med 1984; 25: 1023-30.
    Google Scholar
  • R58 Lim C. B, Han K. S, Hawman E. G, Jaszczak R. J. Image noise, resolution, and lesion detectability in single photon emission CT. IEEE Trans, nucl. Sei 1982; NS-29 500-5.
    Google Scholar
  • R59 Lim C. B, Gottschalk S, Walker R. et al.: Triangular SPECT system for 3-D total organ volume imaging: Design concepts and preliminary imaging results. IEEE Trans, nucl. Sei 1985; NS-32 741-7.
    Google Scholar
  • R60 Loo L. D, Doi K, Metz C. E. A comparison of physical image quality indices and observer performance in the radiographic detection of nylon beads. Phys. Med. Biol 1984; 29: 837-56.
    CrossrefGoogle Scholar
  • R61 Madson M. T, Park C. H. Enhancement of SPECT images by Fourier filtering the projection image set. J. nucl. Med 1985; 26: 395-402.
    Google Scholar
  • R62 Mazziotta J. C, Phelps M. E, Plummer D, Kuhl D. E. Quantitation in positron emission computed tomography: V. Physical-anatomical effects. J. Comp. Assist. Tom 1981; 5: 734-43.
    Google Scholar
  • R63 Metz C. E, Goodenough D. J. On failure to improve observer performance with scan smoothing: A rebuttal. J. nucl. Med 1973; 14: 873-6.
    Google Scholar
  • R64 Metz C. E, Beck R. N. Quantitative effects of stationary linear image processing on noise and resolution of structure in radionuclide images. J. nucl. Med 1974; 15: 164-70.
    Google Scholar
  • R65 Miller M. I, Snyder D. L, Miller T. R. Maximum-likelihood reconstruction for single-photon emission computed tomography. IEEE Trans, nucl. Sei 1985; NS-32 769-78.
    Google Scholar
  • R66 Moore S. C, Brunelle J. A, Kirsch C. M. Quantitative multi-detector ECT using iterative attenuation compensation. J. nucl. Med 1982; 23: 706-14.
    Google Scholar
  • R67 Moore S. C. Attenuation compensation in single photon emission computed tomography. In: Emission Computed Tomography. Ell P. H, Holman B. L. eds 339-60 University Press; Oxford: 1982
    Google Scholar
  • R68 Moore S. C, Mtiller S. P. Inversion of the Radon transform for a multidetector, point-focused SPECT brain scanner. Phys. Med. Biol 1986; 31: 207-21.
    CrossrefGoogle Scholar
  • R69 Moore S. C, Müller S. P, Kijewski M. F, Holman B. L. The axial aperture in SPECT. J. nucl. Med 1986; 27: 930-1.
    Google Scholar
  • R70 Mühllehner G. Effect of resolution improvement on required count density in ECT imaging. A computer simulation. Phys. Med. Biol 1984; 30: 163-73.
    Google Scholar
  • R71 Müller S. P, Pollak J. F, Kijewski M. F, Holman B. L. Collimator selection for SPECT brain imaging: The advantage of high resolution. J. nucl. Med 1986; 27: 1729-38.
    Google Scholar
  • R72 Müller S. P, Kijewski M. F, Moore S. C, Holman B. L. Maximum likelihood estimation of regional activity. J. nucl. Med 1986; 27: 895.
    Google Scholar
  • R73 Müller S. P, Moore S. C, Holman B. L. Performance of a multidetector brain scanner compared to a rotating gammacamera system for the same scan task. In Amphetamines and pH-Shift Agents for Brain Imaging. Biersack H. J, Winkler C. eds 85-95 de Gruyter, Berlin; 1986
    Google Scholar
  • R74 Nguyen N. H, Majewski S, Sauli F. An efficient gaseous detector with good low-energy resolution for <50 keV imaging. J. nucl. Med 1979; 20: 335-40.
    Google Scholar
  • R75 Peyrin F. C. The generalized back projection theorem for cone beam reconstruction. IEEE Trans, nucl. Sei 1985; NS-32 1512-9.
    Google Scholar
  • R76 Phelps M. E, Huang S. C, Hoffman E. J, Plummer D, Carson R. An analysis of signal amplification using small detectors in positron emission tomograph. J. Comp. Assist. Tom 1982; 6: 551-6.
    Google Scholar
  • R77 Riederer S. J, Pelc N. J, Chesler D. A. The noise power spectrum in computed x-ray tomography. Phys. Med. Biol 1978; 23: 446-54.
    CrossrefGoogle Scholar
  • R78 Rogers W. L, Clinthorne N. H, Stamos J. SPRINT: A stationary detector single photon ring tomograph for brain imaging. IEEE Trans. Med. Im 1982; MI-1 63-8.
    Google Scholar
  • R79 Rossman K. Point spread-function line spread-function modulation transfer function. Tools for the study of imaging systems. Radiology 1969; 93: 257-72.
    CrossrefGoogle Scholar
  • R80 Schlosser P. A, Miller D. W, Gerber M. S. et al.: A practical gamma-ray camera system using high-purity germanium. IEEE Trans, nucl. Sei 1974; NS- 21 658-67.
    Google Scholar
  • R81 Shepp L. A, Logan B. F. The Fourier reconstruction of a head section. IEEE Trans, nucl. Sei 1974; NS-21 21-43.
    Google Scholar
  • R82 Shepp L. A, Stein J. A. Simulated reconstruction artefacts in computerized x-ray tomography. In Reconstruction Tomography in Diagnostic Radiology and Nuclear Medicine. Ter-Pogossian M. M. ed 33-48 University Park Press; Baltimore: 1977
    Google Scholar
  • R83 Shepp L. A, Vardi Y. Maximum likelihood reconstruction for emission tomography. IEEE Trans. Med. Im 1982; MI-1 113-22.
    Google Scholar
  • R84 Singh M, Doria D. Germanium- scintillation camera coincidence detection studies for imaging single photon emitters. IEEE Trans, nucl. Sei 1984; NS-31 594-8.
    Google Scholar
  • R85 Smith B. D. Image reconstruction from cone-beam-projections: Necessary and sufficient conditions and reconstruction methods. IEEE Trans. Med. Im 1985; MI-4 14-25.
    Google Scholar
  • R86 Smith W. E, Barrett H. H, Paxman R. G. Reconstruction of objects from coded images by simulated annealing. Opt. Lett 1983; 8: 196.
    Google Scholar
  • R87 Snyder D. L, Miller M. I. The use of sieves to stabilize images produced with the EM algorithm for emission tomography. IEEE Trans, nucl. Sei. 1985 NS-32
    Google Scholar
  • R88 Sorenson J. A. In Instrumentation in Nuclear Medicine. Vol. 2 Hine G. J, Sorenson J. A. eds 311-48 Academic Press; New York: 1974
    Google Scholar
  • R89 Tanaka E. Quantitative image reconstruction with weighted backprojection for single photon emission computed tomography. J. Comp. Assist. Tom 1983; 7: 692-700.
    Google Scholar
  • R90 Tsui B. M. W, Metz C. E, Atkins F. B, Starr S. J, Beck R. N. A comparison of optimum detector spatial resolution in nuclear imaging based on statistical theory and on observer performance. Phys. Med. Biol 1978; 23: 654-76.
    CrossrefGoogle Scholar
  • R91 Tsui B. M. W, Metz C. E, Beck R. N. Optimum detector spatial resolution for discriminating between tumor uptake distributions in scintigraphy. Phys. Med. Biol 1983; 28: 775-788.
    CrossrefGoogle Scholar
  • R92 Tretiak O, Metz C. The exponential radon transform. SIAM J. appl. Math 1980; 39: 341-54.
    CrossrefGoogle Scholar
  • R93 Van Trees H. L. Estimation in nonwhite Gaussian noise. In Detection, Estimation and Modulation Theory, Part I. 287-333 Wiley, New York; 1986
    Google Scholar
  • R94 Wagner R. F. Decision theory and the detail signal-to-noise ratio of Otto Schade. Phot. Sei. Eng 1978; 22: 41-6.
    Google Scholar
  • R95 Wagner R. F, Brown D. G, Pastel M. S. Application of information theory to the assessment of computed tomography. Med. Phys 1979; 6: 83-94.
    CrossrefGoogle Scholar
  • R96 Wagner R. F, Barnes G. T, Askins B. S. Effect of reduced scatter on radiographic information content patient exposure: A quantitative demonstration. Med. Phys 1980; 7: 13-8.
    CrossrefGoogle Scholar
  • R97 Wagner R. F, Brown D. G. Unified SNR analysis of medical imaging systems. Phys. Med. Biol 1985; 30: 489-518.
    CrossrefGoogle Scholar
  • R98 Walters T. E, Simon W, Chesler D. A, Correia J. A. Attenuation correction in gamma emission computed tomography. J. Comp. Assist. Tom 1981; 5: 89-94.
    Google Scholar
  • R99 Winchell H. S, Baldwin R. M, Lin T. H. Development of 1-123 labeled amines for brain studies: Localization of 1-123 iodophenyl-I-123 p-iodoamphet- amine in rat brains. J. nucl. Med 1980; 21: 940-6.
    Google Scholar
  • R100 Winchell H. S, Horst W. D, Braun L. et al.: N-isopropyl-I-123 p-iodoampheta- mine: Single pass brain uptake and washout; binding to brain synaptosomes and localization in dog and monkey brain. J. nucl. Med 1980; 21: 947-52.
    Google Scholar
  • R101 Esser T. D, Alderson P. O, Mitnick R. J. et al. Angled collimator SPECT (A-SPECT: an improved approach to cranial single photon emission tomography). J. Nucl. Med 1984; 25: 805-9.
    Google Scholar
  • R102 Macey D. J, DeNardo G. L, DeNardo S. J. et al.: Comparison of low- and medium energy collimators for SPECT imaging with iodine-123-labeled antibodies. J. Nucl. Med 1986; 27: 1467-74.
    Google Scholar
  • R103 Polak J. F, English R. J, Holman B. L. et al.: Performance of collimators used for tomographic imaging of 1-123 contaminated with 1-124. J. Nucl. Med 1983; 24: 1065-9.
    Google Scholar
  • R104 Polak J. F, Holman B. L, Moretti J. L. et al.: 1-123 brain imaging with a rotating gamma camera and a slant hole collimator. J. Nucl. Med 1984; 25: 495-8.
    Google Scholar