Visualization of Mediastinal Lymph Nodes after Intraperitoneal Administration of ^99mTc-Sulfur Colloid^[*]

Summary

Mediastinal lymph nodes have been demonstrated in a woman following intraperitoneal administration of ^99mTc-sulfur colloid. Rapid uptake of the material in the lymphatics on the undersurface of the diaphragm resulted in substantial concentration of radioactivity in the lymph nodes in approximately 2½ hours.

Les ganglions lymphatiques médiastinaux ont été mis en évidence après injection intrapéritonéale de ^99mTc-S. Par suite de l’absorption rapide du colloïde dans les vaisseaux lymphatiques subdiaphragmatiques, on note après 2½ heures une importante radioactivité au niveau des ganglions lymphatiques.

Nach intraperitonealer Injektion von ^99mTc-Schwefelkolloid wurden mediastinale Lymphknoten in einer Patientin demonstriert. Die schnelle Absorption des Kolloids in die Lymphgefäße an der unteren Seite des Zwerchfells resultierte in einer beträchtlichen Aufnahme des radioaktiven Materials in den Lymphknoten in 2½ Stunden.

^* Research supported by the U.S. Atomic Energy Commission.

• References

• 1 Kazem I, Antoniades J, Brady L. W, Faust D. S, Croll M. N, Lightfoot D. Clinical evaluation of lymph node scanning utilizing colloidal gold 198. Radiology 1968; 90: 905.
• 2 Schenck P, zum Winkel K, Becker J. Die Szintigraphie des parasternalen Lymphsystems. Nucl.-Med. (Stuttg.) 1966; 5: 388.
• 3 Hauser W, Atkins H. L, Richards P. Lymph node scanning with^99mTc-sulfur colloid. Radiology 1969; 92: 1369.
• 4 Müller J. H. Intraperitoneal application of radioactive colloids. In Therapeutic Use of Artificial Radioisotopes Hahn P. F. ed. John Wiley and Sons; New York: 1956: 269.
• 5 Meneely G. R, Auerbach S. H, Woodcock C. C, Kory R. C, Hahn P. F. Transbronchial instillation of radioactive gold colloid in the lung of the dog. Distribution studies, survival and pathology. Am J. Med. Sei 1953; 225: 172.
• 6 Delaloye B, Magnenat P. La lymphographie indirecte et son intérêt en oncologic. In Medical Radioisotope Scanning. Vol. II I.A.E.A.; Vienna: 1964: 227-236.
• 7 HoChoi S, Gordon W, Sheehan F. R, Bender M. A. Radioisotope scanning of the mediastinal lymphatics in animals. Acta Radiol. (Stockh.), Diagnosis 1963; 1: 229.
• 8 Höfer R, Benzer H. Die indirekte Lymphographie der Lunge. In Radioaktive. Isotope in Klinik und Forschung, Band VII Fellinger K, Höfer R. eds. Urban & Schwarzenberg; München—Berlin—Wien: 1967: 410.
• 9 Anghilerî L. J. Uptake of colloidal chromic phosphate in the mediastinal lymph nodes. Therapeutic possibilities. Acta Radiol. (Stockh.), Therapy, Phys. Biol 1968; 7: 202.
• 10 Sahavendan V. Das mediastinale Lymphknotenscanning. In: Radioisotope in der Lokalisationsdiagnostik. Schattauer; Stuttgart: 1967: 519.
• 11 Allen L. On the penetrability of the lymphatics of the diaphragm. Anat. Record 1956; 124: 639.
• 12 Allen L, Weatherford T. Role of fenestrated basement membrane in lymphatic absorption from peritoneal cavity. Am. J. Physiol 1959; 197: 551.
• 13 Liley A. W. Intrauterine transfusion of foetus in haemolytic disease. Brit. Med. J 1963; 2: 1107.