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Tierarztl Prax Ausg K Kleintiere Heimtiere 2008; 36(06): 399-404
DOI: 10.1055/s-0038-1622701
HUND/KATZE
Schattauer GmbH

Immunbedingte Neutropenie bei einem Malteser-Rüden

Immune-mediated neutropenia in a Maltese dog
M. Kessler
1   Tierärztliche Klinik für Kleintiere Hofheim, Gemeinschaftspraxis Dr. Kessler, Dr. Kosfeld, Dr. Tassani-Prell, Dr. Bessmann, Dr. Rupp
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Further Information

Publication History

Eingegangen:27 April 2007

akzeptiert:18 December 2007

Publication Date:
04 January 2018 (online)

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Zusammenfassung:

Gegenstand und Ziel: Der Fallbericht erörtert diagnostisches Vorgehen und Therapie bei einem Hund mit einer immunbedingten Neutropenie. Material und Methode: Beschreibung der Krankengeschichte eines 4,5 Jahre alten Rüden, der 14 Tage nach einer Auffrischungsimpfung mit Symptomen einer Septikämie und hochgradiger Neutropenie vorgestellt wurde. Ergebnisse: Nach Ausschluss anderer Erkrankungen und anhand des Nachweises von Antikörpern auf den neutrophilen Granulozyten wurde eine immunbedingte Neutropenie diagnostiziert und erfolgreich mit Kortikosteroiden behandelt. Schlussfolgerungen und Klinische Relevanz: Immunbedingte Neutropenien sind beim Hund selten und können unterschiedliche Ursachen aufweisen. Das Auftreten der immunbedingten Neutropenie nach einer Auffrischungsimpfung könnte im vorliegenden Fall auf eine impfassoziierte Ätiologie hindeuten.

Summary

Objective: This case report details the diagnostic approach and therapy in a patient with immune-mediated neutropenia. Material and methods: History of a 4.5-year-old male dog presented 14 days after routine booster vaccination with symptoms of septicaemia and severe neutropenia. Results: By excluding other causes of neutropenia and detection of antibodies on the surface of neutrophils an immune-mediated neutropenia was diagnosed and successfully treated with corticosteroids. Conclusion and Clinical relevance: Immune-mediated neutropenias in dogs are rare and can be associated with various etiologies. Since the immune-mediated neutropenia in this case occurred shortly after a vaccination, an etiologic connection was suspected.

Schlüsselwörter

Hund - immunvermittelte Erkrankungen - Neutropenie - antigranulozytäre Antikörper

Key words

Dog - immune-mediated diseases - neutropenia - anti-granulocytic antibodies
 

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