99mTc-Unithiol Complex, a New Radiopharmaceutical for Kidney Scintigraphy

M. Ogiński; I. Giryn; T. Piatek

doi:10.1055/s-0037-1620936

Nuklearmedizin - NuclearMedicine, Inhaltsverzeichnis

Nuklearmedizin 1980; 19(02): 91-92
DOI: 10.1055/s-0037-1620936

Originalarbeiten – Original Articles

Schattauer GmbH

^99mTc-Unithiol Complex, a New Radiopharmaceutical for Kidney Scintigraphy

IV. Autoradiographic Localisation of its Cellular Distribution in the Kidney ^99mTc-Uni thiol-Komplex, ein neues Radiopharmazeutikum für die NierenszintigraphieIV. Autoradiographische Lokalisierung seiner zellularen Verteilung in der Niere

M. Ogiński

¹ From the Department of Nuclear Medicine and Radiobiology and the Department of Oncology, Medical Academy, Lodz, Poland

,

I. Giryn

¹ From the Department of Nuclear Medicine and Radiobiology and the Department of Oncology, Medical Academy, Lodz, Poland

,

T. Piatek

¹ From the Department of Nuclear Medicine and Radiobiology and the Department of Oncology, Medical Academy, Lodz, Poland

› Institutsangaben

Abstract

Summary

The distribution of ^99mTc-Unithiol complex was studied by macro-autoradiography in rats and in rabbit kidneys, and the presence of activity in the renal cortex was easily demonstrated. Using micro-autoradiography, the accumulation of activity in various parts of the nephron was observed to concentrate in the cells of the proximal and distal tubuli to a larger extent than in the glomeruli.

Zusammenfassung

Die Verteilung des ^99mTc-Unithiol-Komplexes wurde makro-autoradiographisch in Ratten und in der Kaninchenniere untersucht, wobei das Vorhandensein von Radioaktivität in der Nierenrinde leicht nachgewiesen werden konnte. Mittels Mikro-Autoradiographie konnte gezeigt werden, daß die Aktivität in den Zellen der proximalen und distalen Tubuli stärker konzentriert wird als in den Glomeruli.

Volltext

Referenzen

References
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