Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00035024.xml
Download PDF
Thromb Haemost 2001; 86(05): 1338-1339
DOI: 10.1055/s-0037-1616074
DOI: 10.1055/s-0037-1616074
Letters to the Editor
The P2Y1 Receptor Antagonist Adenosine-2’,5’-Diphosphate Non-selectively Antagonizes the Platelet P2X1 Ion Channel
Further Information
Publication History
Received
25 June 2001
Accepted
26 June 2001
Publication Date:
13 December 2017 (online)
-
References
- 1 Ravelic V, and Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 1998; 50: 413-92.
- 2 Cattaneo M, Gachet C. ADP receptors and clinical bleeding disorders. Arterioscler Thromb Vasc Biol 1999; 19: 2281-5.
- 3 Mahaut-Smith MP, Ennion SJ, Rolf MG, Evans RJ. ADP is not an agonist at P2X1 receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets. Br J Pharmacol 2000; 131: 108-14.
- 4 Rolf MG, Brearley CA, Mahaut-Smith MP. Platelet shape change evoked by selective activation of P2X1 purinoceptors with α,β-methylene ATP. Thromb Haemost 2001; 85: 303-8.
- 5 Oury C, Toth-Zsamboki E, Thys C, Tytgat J, Vermylen J, Hoylaerts M. The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen. Thromb Haemost 2001; 86: 1264-71.
- 6 Boyer JL, Mohanram A, Camaioni E, Jacobson KA, Harden TK. Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2′-deoxyadenosine 3′,5′-biphosphate. Br J Pharmacol 1998; 124: 1-3.
- 7 Brown SG, King BF, Kim YC, Jang SY, Burnstock G, Jacobson KA. Activity of novel adenine nucleotide derivatives as agonists and antagonists at recombinant rat P2X receptors. Drug Dev Res 2000; 49: 253-9.
- 8 Boyer JL, Romero-Avila T, Schchter JB, Harden TK. Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol 1996; 50: 1323-9.
- 9 Eckly A, Gendrault J-L, Hechler B, Cazenave J-P, Gachet C. Differential involvement of the P2Y1 and P2YT receptors in the morphological changes of platelet aggregation. Thromb Haemost 2001; 85: 694-701.
- 10 Oury C, Toth-Zsamboki E, Van Geet C, Thys C, Wei L, Nilius B, Vermylen J, Hoylaerts MF. A natural dominant negative P2X1 receptor due to deletion of a single amino acid residue. J Biol Chem 2000; 275: 22611-4.
- 11 Deckmyn H, Stanssens P, Hoet B, Declerck PJ, Lauwereys M, Gansemans Y, Tornai I, Vermylen J. An echistatin-like Arg-Gly-Asp (RGD)-containing sequence in the heavy chain CDR3 of a murine monoclonal antibody that inhibits human platelet glycoprotein IIb/IIIa function. Br J Haematol 1994; 87: 562-71.