Digestive Disease Interventions 2017; 01(03): 147-154
DOI: 10.1055/s-0037-1607434
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Imaging of Liver Metastases

Pratik Wagle
2   Ohio University Heritage College of Osteopathic Medicine, Athens, Ohio
,
Lakshmi Ananthakrishnan
3   Department of Radiology, UT Southwestern Medical Center, Dallas, Texas
,
Christopher P. Coppa
1   Department of Radiology, Cleveland Clinic Foundation, Cleveland, Ohio
› Author Affiliations
Further Information

Publication History

11 July 2017

05 September 2017

Publication Date:
07 November 2017 (online)

Abstract

The evaluation of liver metastases using computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography-CT (PET-CT) is discussed in this article. PET-MR and multienergy CT are newer techniques gaining appeal in the assessment of liver metastases and have also been reviewed.

 
  • References

  • 1 Namasivayam S, Martin DR, Saini S. Imaging of liver metastases: MRI. Cancer Imaging 2007; 7: 2-9
  • 2 Danet IM, Semelka RC, Leonardou P. , et al. Spectrum of MRI appearances of untreated metastases of the liver. AJR Am J Roentgenol 2003; 181 (03) 809-817
  • 3 Gore RM, Thakrar KH, Wenzke DR, Newmark GM, Mehta UK, Berlin JW. That liver lesion on MDCT in the oncology patient: is it important?. Cancer Imaging 2012; 12: 373-384
  • 4 Sica GT, Ji H, Ros PR. CT and MR imaging of hepatic metastases. AJR Am J Roentgenol 2000; 174 (03) 691-698
  • 5 Newatia A, Khatri G, Friedman B, Hines J. Subtraction imaging: applications for nonvascular abdominal MRI. AJR Am J Roentgenol 2007; 188 (04) 1018-1025
  • 6 Liu PS. Liver mass evaluation in patients without cirrhosis: a technique-based method. Radiol Clin North Am 2015; 53 (05) 903-918
  • 7 Vogl TJ, Kümmel S, Hammerstingl R. , et al. Liver tumors: comparison of MR imaging with Gd-EOB-DTPA and Gd-DTPA. Radiology 1996; 200 (01) 59-67
  • 8 Ringe KI, Husarik DB, Sirlin CB, Merkle EM. Gadoxetate disodium-enhanced MRI of the liver: part 1, protocol optimization and lesion appearance in the noncirrhotic liver. AJR Am J Roentgenol 2010; 195 (01) 13-28
  • 9 Donati OF, Hany TF, Reiner CS. , et al. Value of retrospective fusion of PET and MR images in detection of hepatic metastases: comparison with 18F-FDG PET/CT and Gd-EOB-DTPA-enhanced MRI. J Nucl Med 2010; 51 (05) 692-699
  • 10 Siegelman ES, Chauhan A. MR characterization of focal liver lesions: pearls and pitfalls. Magn Reson Imaging Clin N Am 2014; 22 (03) 295-313
  • 11 Curvo-Semedo L, Brito JB, Seco MF, Costa JF, Marques CB, Caseiro-Alves F. The hypointense liver lesion on T2-weighted MR images and what it means. Radiographics 2010; 30 (01) e38
  • 12 Moore WA, Khatri G, Madhuranthakam AJ, Sims RD, Pedrosa I. Added value of diffusion-weighted acquisitions in MRI of the abdomen and pelvis. AJR Am J Roentgenol 2014; 202 (05) 995-1006
  • 13 Taouli B, Koh DM. Diffusion-weighted MR imaging of the liver. Radiology 2010; 254 (01) 47-66
  • 14 Adam SZ, Miller FH. Imaging of the liver following interventional therapy for hepatic neoplasms. Radiol Clin North Am 2015; 53 (05) 1061-1076
  • 15 Matthews R, Choi M. Clinical Utility of Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI) in Gastrointestinal Cancers. Diagnostics (Basel) 2016; 6 (03) E35
  • 16 Abeloff M. D's liver metastases. In: Abeloffs Clinical Oncology. Philadelphia, PA: Churchill Livingstone/Elsevier; 2014: 778-793
  • 17 Sacks A, Peller PJ, Surasi DS, Chatburn L, Mercier G, Subramaniam RM. Value of PET/CT in the management of liver metastases, part 1. AJR Am J Roentgenol 2011; 197 (02) W256-W259
  • 18 Sharma B, Martin A, Zerizer I. Positron emission tomography-computed tomography in liver imaging. Semin Ultrasound CT MR 2013; 34 (01) 66-80
  • 19 Paspulati RM, Gupta A. PET/MR imaging in cancers of the gastrointestinal tract. PET Clin 2016; 11 (04) 403-423
  • 20 Nielsen K, Scheffer HJ, Pieters IC. , et al. The use of PET-MRI in the follow-up after radiofrequency- and microwave ablation of colorectal liver metastases. BMC Med Imaging 2014; 14: 27
  • 21 Fowler KJ, Maughan NM, Laforest R. , et al. PET/MRI of hepatic 90Y microsphere deposition determines individual tumor response. Cardiovasc Intervent Radiol 2016; 39 (06) 855-864
  • 22 Fraum TJ, Owen JW, Fowler KJ. Beyond histologic staging: emerging imaging strategies in colorectal cancer with special focus on magnetic resonance imaging. Clin Colon Rectal Surg 2016; 29 (03) 205-215
  • 23 McCollough CH, Leng S, Yu L, Fletcher JG. Dual- and multi-energy CT: principles, technical approaches, and clinical applications. Radiology 2015; 276 (03) 637-653
  • 24 Marin D, Ramirez-Giraldo JC, Gupta S. , et al. Effect of a noise-optimized second-generation monoenergetic algorithm on image noise and conspicuity of hypervascular liver tumors: an in vitro and in vivo study. AJR Am J Roentgenol 2016; 206 (06) 1222-1232
  • 25 Shuman WP, Green DE, Busey JM. , et al. Dual-energy liver CT: effect of monochromatic imaging on lesion detection, conspicuity, and contrast-to-noise ratio of hypervascular lesions on late arterial phase. AJR Am J Roentgenol 2014; 203 (03) 601-606
  • 26 Caruso D, De Cecco CN, Schoepf UJ. , et al. Can dual-energy computed tomography improve visualization of hypoenhancing liver lesions in portal venous phase? Assessment of advanced image-based virtual monoenergetic images. Clin Imaging 2017; 41: 118-124
  • 27 Altenbernd J, Wetter A, Forsting M, Umutlu L. Treatment response after radioembolisation in patients with hepatocellular carcinoma-An evaluation with dual energy computed-tomography. Eur J Radiol Open 2016; 3: 230-235
  • 28 Lee JA, Jeong WK, Kim Y. , et al. Dual-energy CT to detect recurrent HCC after TACE: initial experience of color-coded iodine CT imaging. Eur J Radiol 2013; 82 (04) 569-576
  • 29 Lee SH, Lee JM, Kim KW. , et al. Dual-energy computed tomography to assess tumor response to hepatic radiofrequency ablation: potential diagnostic value of virtual noncontrast images and iodine maps. Invest Radiol 2011; 46 (02) 77-84
  • 30 Dai X, Schlemmer H-P, Schmidt B. , et al. Quantitative therapy response assessment by volumetric iodine-uptake measurement: initial experience in patients with advanced hepatocellular carcinoma treated with sorafenib. Eur J Radiol 2013; 82 (02) 327-334
  • 31 Apfaltrer P, Meyer M, Meier C. , et al. Contrast-enhanced dual-energy CT of gastrointestinal stromal tumors: is iodine-related attenuation a potential indicator of tumor response?. Invest Radiol 2012; 47 (01) 65-70