Diabetologie und Stoffwechsel 2017; 12(03): 222-228
DOI: 10.1055/s-0037-1603549
Typ-1-Diabetes
Georg Thieme Verlag KG Stuttgart · New York

Oxidized LDL as a biomarker in metabolic syndrome

W Ali
1   King George's Medical University, Department of Pathology, Lucknow, India
,
UP Kushwaha
1   King George's Medical University, Department of Pathology, Lucknow, India
,
W Mohd
1   King George's Medical University, Department of Pathology, Lucknow, India
› Author Affiliations
Further Information

Publication History

Publication Date:
06 July 2017 (online)

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    Objective:

    To study the correlation of lipids and lipoprotein With LDL in study subjects.

    Material and methods:

    Total 104 symptomatic cases of either age between 20 – 80 years were recruited, of which, 10 were type 2 diabetes mellitus (type 2DM), 63 were with metabolic syndrome (MS), and 31 were type 2 diabetes Mellitus with hypertension (Type-2DM + HT). Total 20, age and sex matched normal healthy subjects were recruited and served as control group. Thus, studymaking of totally 124 subjects.

    Results:

    Comparing the Mean OxLDL of the four groups, ANOVA was significantly (p < 0.001) different mean oxLDL among the groups. Further, Bonferroni test, that the mean OxLDL raised significantly (P < 0.001) in cases (Type-2DM, MS and Type-2DM + HT).

    Conclusion:

    It is concluded that oxLDL may be a predictive biomarker in metabolic syndrome individuals.

    Keywords:

    Ox -LDL, HDL, VLDL, Diabetes mellitus, Metabolic Syndrome.


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